USP32 Antibody (F-3): sc-376491

USP32 Antibody (F-3) is a mouse monoclonal IgG1 antibody that detects USP32 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). USP32, also known as ubiquitin specific peptidase 32 or NY-REN-60, is a crucial 1,604 amino acid protein characterized by the presence of one dual specificity phosphatase (DUSP) domain and three EF-hand calcium binding domains. USP32 is primarily localized to cellular membranes in a lipid-anchored manner and is expressed across all normal tissues, highlighting USP32′s fundamental role in cellular function. USP32 is involved in the deubiquitination process, where USP32 catalyzes the conversion of a ubiquitin C-terminal thioester to free ubiquitin and a thiol, a reaction that is vital for regulating various cellular processes such as signal transduction, transcriptional activation, and cell cycle progression. USP32′s ability to modulate the ubiquitin pathway underscores USP32′s importance in maintaining cellular homeostasis and responding to stress signals, making USP32 a significant target for research in cancer and other diseases where ubiquitin signaling is disrupted. Anti-USP32 antibody (F-3) provides a reliable tool for researchers aiming to explore the functional implications of USP32 in various biological contexts.

The preferred USP32 antibody is USP32 Antibody (A-10): sc-374465.