ULBP3 Antibody (YY42): sc-80420
- ULBP3 Antibody (YY42) is a mouse monoclonal IgG2a provided at 100 µg/ml
- raised against BaF/3 cells transfected with ULBP3 of human origin
- recommended for detection of ULBP3 of human origin by FCM; non cross-reactive with ULBP1 or ULBP2
- also provided azide-free for blocking, sc-80420 L, 100 µg/0.1 ml
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ULBP3 Antibody (YY42). This work is in progress.
ULBP3 Antibody (YY42) is a mouse monoclonal IgG2a antibody that detects ULBP3 in human samples through flow cytometry (FCM). ULBP3, a member of the UL16 binding protein family, plays a crucial role in the immune response by acting as a ligand for the activating receptor NKG2D/DAP10, which is essential for the activation of natural killer (NK) cells and CD8+ T cells. This interaction triggers the secretion of cytokines, including interferon-gamma, and promotes the lysis of tumor cells, highlighting ULBP3′s importance in immune surveillance and tumor immunity. ULBP3 is primarily located on the surface of stressed or transformed cells, where immune cells can recognize ULBP3, thus facilitating the elimination of potentially harmful cells. Additionally, ULBP3 is glycosylated, which can influence stability and interaction with receptors, further underscoring the significance of post-translational modifications in modulating immune responses. Anti-ULBP3 antibody (YY42) is an invaluable tool for researchers studying the mechanisms of immune activation and the role of ULBPs in cancer immunology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ULBP3 Antibody (YY42) | sc-80420 | 100 µg/ml | $322.00 | |||
ULBP3 Antibody (YY42) L | sc-80420 L | 100 µg/0.1 ml | $322.00 |