Uev1A/Mms2 Antibody (F-11): sc-377337
- Uev1A/Mms2 Antibody (F-11) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- raised against amino acids 1-145 representing full length Mms2 of human origin
- recommended for detection of Uev1A isoforms 1, 2, 3, 4 and 5 and Mms2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Uev1A/Mms2 Antibody (F-11) for WB applications. This reagent is now offered in a bundle with Uev1A/Mms2 Antibody (F-11) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Uev1A/Mms2 Antibody (F-11) is a mouse monoclonal IgG3 antibody that detects Uev1A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Uev1A, also known as ubiquitin-conjugating enzyme E2 variant 1, plays a crucial role in protein degradation and cellular signaling pathways, particularly in DNA repair and stress responses. Although Uev1A lacks the critical cysteine residue necessary for traditional ubiquitin-conjugating activity, Uev1A collaborates with TRAF6 to facilitate unique polyubiquitin chains linked through Lysine 63, which are essential for various cellular processes, including inflammatory response modulation and genomic stability maintenance. Uev1A localization to the nucleus, while excluding nucleolar regions, underscores Uev1A′s importance in nuclear signaling pathways and highlights Uev1A′s potential as a therapeutic target in cancer and other diseases. anti-Uev1A/Mms2 antibody (F-11) serves as an invaluable tool for researchers investigating ubiquitin-like proteins in cellular function and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Uev1A/Mms2 Antibody (F-11) | sc-377337 | 200 µg/ml | $322.00 | |||
Uev1A/Mms2 Antibody (F-11): m-IgGκ BP-HRP Bundle | sc-552154 | 200 µg Ab; 40 µg BP | $361.00 |