Uev1A/Mms2 Antibody (C-12): sc-377223
- Uev1A/Mms2 Antibody (C-12) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 1-145 representing full length Mms2 of human origin
- recommended for detection of Uev1A isoforms 1-5 and Mms2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Uev1A/Mms2 Antibody (C-12) for WB applications. This reagent is now offered in a bundle with Uev1A/Mms2 Antibody (C-12) (see ordering information below).
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SEE ALSO...
Uev1A/Mms2 Antibody (C-12) is a mouse monoclonal IgG2a antibody that detects Uev1A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Uev1A, also known as ubiquitin-conjugating enzyme E2 variant 1, plays a crucial role in protein degradation and cellular signaling pathways, particularly through interaction with TRAF6 to form unique polyubiquitin chains linked via Lysine 63 of ubiquitin. This specific linkage is vital for various cellular processes, including DNA repair and modulation of inflammatory responses, highlighting Uev1A′s importance in maintaining cellular homeostasis and responding to stress signals. Notably, Uev1A is localized primarily in the nucleus, excluding nucleolar regions, suggesting a specialized role in nuclear signaling and regulation. anti-Uev1A/Mms2 antibody (C-12) serves as an essential tool for researchers investigating ubiquitin signaling mechanisms and their implications in diseases such as cancer and neurodegeneration.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Uev1A/Mms2 Antibody (C-12) | sc-377223 | 200 µg/ml | $322.00 | |||
Uev1A/Mms2 Antibody (C-12): m-IgG Fc BP-HRP Bundle | sc-540705 | 200 µg Ab; 10 µg BP | $361.00 |