UBE2L3 Antibody (A-5): sc-376517
- UBE2L3 Antibody (A-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 101-139 near the C-terminus of UBE2L3 of human origin
- recommended for detection of UBE2L3 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for UBE2L3 Antibody (A-5) for WB applications. These reagents are now offered in bundles with UBE2L3 Antibody (A-5) (see ordering information below).
UBE2L3 Antibody (A-5) is a mouse monoclonal IgG1 antibody that detects UBE2L3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). UBE2L3, also known as UBCH7, is a crucial E2 ubiquitin-conjugating enzyme that plays a significant role in the ubiquitin-proteasome system, which is essential for regulating protein degradation and maintaining cellular homeostasis. UBE2L3 is primarily located in the cytoplasm, where UBE2L3 facilitates the transfer of ubiquitin to target proteins, thereby marking them for degradation or altering their function. Proper functioning of UBE2L3 is vital, as dysregulation of this pathway can lead to various diseases, including cancer, by allowing the accumulation of misfolded or damaged proteins. UBE2L3 has been shown to interact with several important proteins, including the tumor suppressor protein TSSC5 and components involved in the degradation of c-fos and NFκB, highlighting UBE2L3′s role in critical cellular processes. Anti-UBE2L3 antibody (A-5) is an invaluable tool for researchers studying the dynamics of protein regulation and the implications of ubiquitination in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBE2L3 Antibody (A-5) | sc-376517 | 200 µg/ml | $322.00 | |||
UBE2L3 Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-540589 | 200 µg Ab; 10 µg BP | $361.00 | |||
UBE2L3 Antibody (A-5): m-IgG1 BP-HRP Bundle | sc-542225 | 200 µg Ab; 20 µg BP | $361.00 | |||
UBE2L3 (A-5) Neutralizing Peptide | sc-376517 P | 100 µg/0.5 ml | $69.00 |