Ubc12 Antibody (A-6): sc-393765
- Ubc12 Antibody (A-6) is a mouse monoclonal IgG1 κ Ubc12 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 12-37 near the N-terminus of Ubc12 of Saccharomyces cerevisiae origin
- Ubc12 Antibody (A-6) is recommended for detection of Ubc12 of y origin by WB, IP, IF and ELISA
- Anti-Ubc12 Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Ubc12 Antibody (A-6) for WB applications. These reagents are now offered in bundles with Ubc12 Antibody (A-6) (see ordering information below).
Ubc12 Antibody (A-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ubc12 protein of Saccharomyces cerevisiae origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Ubc12 antibody (A-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Ubc12 plays a crucial role in the ubiquitin-like modification process, specifically in the neddylation pathway, where Ubc12 conjugates the ubiquitin-like protein NEDD8 to target proteins, thereby regulating their activity and stability. This modification is essential for various cellular processes, including cell cycle progression, signal transduction, and DNA repair, highlighting Ubc12′s importance in maintaining cellular homeostasis. Additionally, Ubc12 interacts with several key proteins, such as Rub1, Ula1, and Uba3, which are involved in the activation and transfer of NEDD8, further emphasizing Ubc12′s role in the ubiquitin-proteasome system. Understanding Ubc12′s function and interactions is vital for elucidating the mechanisms of protein regulation and degradation in eukaryotic cells, making Ubc12 (A-6) monoclonal antibody an invaluable tool for researchers studying these processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ubc12 Antibody (A-6) | sc-393765 | 200 µg/ml | $322.00 | |||
Ubc12 Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-527712 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ubc12 Antibody (A-6): m-IgG1 BP-HRP Bundle | sc-533085 | 200 µg Ab; 20 µg BP | $361.00 | |||
Ubc12 Antibody (A-6) AC | sc-393765 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Ubc12 Antibody (A-6) HRP | sc-393765 HRP | 200 µg/ml | $322.00 | |||
Ubc12 Antibody (A-6) FITC | sc-393765 FITC | 200 µg/ml | $336.00 | |||
Ubc12 Antibody (A-6) PE | sc-393765 PE | 200 µg/ml | $349.00 | |||
Ubc12 Antibody (A-6) Alexa Fluor® 488 | sc-393765 AF488 | 200 µg/ml | $364.00 | |||
Ubc12 Antibody (A-6) Alexa Fluor® 546 | sc-393765 AF546 | 200 µg/ml | $364.00 | |||
Ubc12 Antibody (A-6) Alexa Fluor® 594 | sc-393765 AF594 | 200 µg/ml | $364.00 | |||
Ubc12 Antibody (A-6) Alexa Fluor® 647 | sc-393765 AF647 | 200 µg/ml | $364.00 | |||
Ubc12 Antibody (A-6) Alexa Fluor® 680 | sc-393765 AF680 | 200 µg/ml | $364.00 | |||
Ubc12 Antibody (A-6) Alexa Fluor® 790 | sc-393765 AF790 | 200 µg/ml | $364.00 | |||
Ubc12 (A-6) Neutralizing Peptide | sc-393765 P | 100 µg/0.5 ml | $69.00 |