TXNDC9 Antibody (C-8): sc-514770
- TXNDC9 Antibody (C-8) is a mouse monoclonal IgG2b κ TXNDC9 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 63-178 mapping within an internal region of TXNDC9 of human origin
- TXNDC9 Antibody (C-8) is recommended for detection of TXNDC9 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TXNDC9 Antibody (C-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TXNDC9 Antibody (C-8) for WB applications. These reagents are now offered in bundles with TXNDC9 Antibody (C-8) (see ordering information below).
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TXNDC9 Antibody (C-8) is a mouse monoclonal IgG2b kappa light chain antibody that detects TXNDC9 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-TXNDC9 antibody (C-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TXNDC9, also known as thioredoxin domain-containing protein 9, plays a crucial role in cellular redox homeostasis by participating in the rearrangement of disulfide bonds, which is essential for proper protein folding and function. TXNDC9 contains a thioredoxin domain that allows for disulfide isomerase activity, facilitating the correct formation of disulfide bonds in various target proteins, thereby influencing critical cellular processes such as cell differentiation and response to oxidative stress. The gene encoding TXNDC9 is located on human chromosome 2, a region associated with various genetic disorders, including Harlequin ichthyosis and Alström syndrome, highlighting TXNDC9′s importance in maintaining cellular integrity and function. TXNDC9 (C-8) antibody serves as an invaluable tool for studying TXNDC9′s role in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TXNDC9 Antibody (C-8) References:
- An evolutionarily conserved gene required for proper microtubule architecture in Caenorhabditis elegans. | Ogawa, S., et al. 2004. Genes Cells. 9: 83-93. PMID: 15009089
- ABCA12 is the major harlequin ichthyosis gene. | Thomas, AC., et al. 2006. J Invest Dermatol. 126: 2408-13. PMID: 16902423
- Spectrum of ALMS1 variants and evaluation of genotype-phenotype correlations in Alström syndrome. | Marshall, JD., et al. 2007. Hum Mutat. 28: 1114-23. PMID: 17594715
- Alström syndrome. | Marshall, JD., et al. 2007. Eur J Hum Genet. 15: 1193-202. PMID: 17940554
- Origin of human chromosome 2: an ancestral telomere-telomere fusion. | IJdo, JW., et al. 1991. Proc Natl Acad Sci U S A. 88: 9051-5. PMID: 1924367
- Structural and functional relations among thioredoxins of different species. | Eklund, H., et al. 1991. Proteins. 11: 13-28. PMID: 1961698
- Thioredoxin and glutaredoxin systems. | Holmgren, A. 1989. J Biol Chem. 264: 13963-6. PMID: 2668278
- Thioredoxin. | Holmgren, A. 1985. Annu Rev Biochem. 54: 237-71. PMID: 3896121
- Protein disulphide isomerase: building bridges in protein folding. | Freedman, RB., et al. 1994. Trends Biochem Sci. 19: 331-6. PMID: 7940678
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TXNDC9 Antibody (C-8) | sc-514770 | 200 µg/ml | $322.00 | |||
TXNDC9 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-524840 | 200 µg Ab, 40 µg BP | $361.00 | |||
TXNDC9 Antibody (C-8): m-IgG2b BP-HRP Bundle | sc-549189 | 200 µg Ab; 10 µg BP | $361.00 | |||
TXNDC9 Antibody (C-8) AC | sc-514770 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TXNDC9 Antibody (C-8) HRP | sc-514770 HRP | 200 µg/ml | $322.00 | |||
TXNDC9 Antibody (C-8) FITC | sc-514770 FITC | 200 µg/ml | $336.00 | |||
TXNDC9 Antibody (C-8) PE | sc-514770 PE | 200 µg/ml | $349.00 | |||
TXNDC9 Antibody (C-8) Alexa Fluor® 488 | sc-514770 AF488 | 200 µg/ml | $364.00 | |||
TXNDC9 Antibody (C-8) Alexa Fluor® 546 | sc-514770 AF546 | 200 µg/ml | $364.00 | |||
TXNDC9 Antibody (C-8) Alexa Fluor® 594 | sc-514770 AF594 | 200 µg/ml | $364.00 | |||
TXNDC9 Antibody (C-8) Alexa Fluor® 647 | sc-514770 AF647 | 200 µg/ml | $364.00 | |||
TXNDC9 Antibody (C-8) Alexa Fluor® 680 | sc-514770 AF680 | 200 µg/ml | $364.00 | |||
TXNDC9 Antibody (C-8) Alexa Fluor® 790 | sc-514770 AF790 | 200 µg/ml | $364.00 |