Twinfilin-1 Antibody (B-7): sc-376468
- Twinfilin-1 Antibody (B-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 175-236 mapping near the C-terminus of Twinfilin-1 of human origin
- recommended for detection of Twinfilin-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for Twinfilin-1 Antibody (B-7) for WB and IHC(P) applications. These reagents are now offered in bundles with Twinfilin-1 Antibody (B-7) (see ordering information below).
QUICK LINKS
Twinfilin-1 Antibody (B-7) is a mouse monoclonal IgG2a antibody that detects Twinfilin-1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Twinfilin-1 is a crucial actin monomer-binding protein that plays a significant role in regulating cytoskeletal dynamics, which is essential for numerous cellular processes such as cell motility, shape maintenance, and division. Twinfilin-1 is primarily located in the cytoplasm, where Twinfilin-1 interacts with actin filaments to prevent their assembly by sequestering actin monomers and inhibiting nucleotide exchange. Proper functioning of Twinfilin-1 is vital, as dysregulation can lead to various cellular dysfunctions and has been implicated in diseases such as cancer and neurodegenerative disorders. Additionally, Twinfilin-1′s activity is modulated by post-translational modifications, including phosphorylation, which can influence binding affinity and localization, further underscoring Twinfilin-1′s importance in cellular signaling pathways. With an ability to bind ADP-G-actin and interact with capping proteins, Twinfilin-1 serves as a key regulator of actin dynamics, making anti-Twinfilin-1 antibody (B-7) an invaluable tool for researchers studying cytoskeletal organization and function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Twinfilin-1 Antibody (B-7) | sc-376468 | 200 µg/ml | $322.00 | |||
Twinfilin-1 Antibody (B-7): m-IgG Fc BP-HRP Bundle | sc-540577 | 200 µg Ab; 10 µg BP | $361.00 | |||
Twinfilin-1 Antibody (B-7): m-IgG2a BP-HRP Bundle | sc-546928 | 200 µg Ab; 10 µg BP | $361.00 |