TudorSN Antibody (F-5): sc-166676
- TudorSN Antibody (F-5) is a mouse monoclonal IgG2b κ TudorSN antibody, cited in 4 publications, provided at 200 µg/ml
- raised against a peptide mapping at the C-terminus of TudorSN of human origin
- TudorSN Antibody (F-5) is recommended for detection of TudorSN of mouse, rat, human and avian origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- TransCruz reagent for ChIP application (sc-166676 X, 200 µg/0.1 ml)
- Anti-TudorSN Antibody (F-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TudorSN Antibody (F-5) for WB and IHC(P) applications. These reagents are now offered in bundles with TudorSN Antibody (F-5) (see ordering information below).
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SEE ALSO...
TudorSN Antibody (F-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects TudorSN protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-TudorSN antibody (F-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TudorSN plays a crucial role in regulating transcriptional activity, particularly in Pim-1 regulation of Myb activity, and acts as a transcriptional activator of EBNA-2. TudorSN interacts with several key proteins, including EAV, NSP1, GTF2E1, and GTF2E2, and forms a ternary complex with Stat6 and POLR2A, which is essential for assembly of the Stat6 transcriptome. The staphylococcal nuclease-like domains of TudorSN directly interact with specific amino acids of CREB-binding protein (CBP), highlighting TudorSN′s importance in mediating IL-4-dependent transcription by facilitating interaction between Stat6 and CBP. This intricate network of interactions underscores TudorSN′s significance in various cellular processes, making TudorSN monoclonal antibody (F-5) a valuable tool for researchers studying gene regulation and transcriptional mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TudorSN Antibody (F-5) References:
- Tudor and nuclease-like domains containing protein p100 function as coactivators for signal transducer and activator of transcription 5. | Paukku, K., et al. 2003. Mol Endocrinol. 17: 1805-14. PMID: 12819296
- Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100. | Tijms, MA. and Snijder, EJ. 2003. J Gen Virol. 84: 2317-2322. PMID: 12917451
- The p100 EBNA-2 coactivator: a highly conserved protein found in a range of exocrine and endocrine cells and tissues in cattle. | Broadhurst, MK., et al. 2005. Biochim Biophys Acta. 1681: 126-33. PMID: 15627504
- The transcriptional co-activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6. | Välineva, T., et al. 2005. J Biol Chem. 280: 14989-96. PMID: 15695802
- Pim-1 kinase and p100 cooperate to enhance c-Myb activity. | Leverson, JD., et al. 1998. Mol Cell. 2: 417-25. PMID: 9809063
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TudorSN Antibody (F-5) | sc-166676 | 200 µg/ml | $316.00 | |||
TudorSN Antibody (F-5): m-IgGκ BP-HRP Bundle | sc-521705 | 200 µg Ab, 40 µg BP | $354.00 | |||
TudorSN Antibody (F-5): m-IgG2b BP-HRP Bundle | sc-548953 | 200 µg Ab; 10 µg BP | $354.00 | |||
TudorSN Antibody (F-5) X | sc-166676 X | 200 µg/0.1 ml | $316.00 | |||
TudorSN Antibody (F-5) AC | sc-166676 AC | 500 µg/ml, 25% agarose | $416.00 | |||
TudorSN Antibody (F-5) HRP | sc-166676 HRP | 200 µg/ml | $316.00 | |||
TudorSN Antibody (F-5) FITC | sc-166676 FITC | 200 µg/ml | $330.00 | |||
TudorSN Antibody (F-5) PE | sc-166676 PE | 200 µg/ml | $343.00 | |||
TudorSN Antibody (F-5) Alexa Fluor® 488 | sc-166676 AF488 | 200 µg/ml | $357.00 | |||
TudorSN Antibody (F-5) Alexa Fluor® 546 | sc-166676 AF546 | 200 µg/ml | $357.00 | |||
TudorSN Antibody (F-5) Alexa Fluor® 594 | sc-166676 AF594 | 200 µg/ml | $357.00 | |||
TudorSN Antibody (F-5) Alexa Fluor® 647 | sc-166676 AF647 | 200 µg/ml | $357.00 | |||
TudorSN Antibody (F-5) Alexa Fluor® 680 | sc-166676 AF680 | 200 µg/ml | $357.00 | |||
TudorSN Antibody (F-5) Alexa Fluor® 790 | sc-166676 AF790 | 200 µg/ml | $357.00 | |||
TudorSN (F-5) Neutralizing Peptide | sc-166676 P | 100 µg/0.5 ml | $68.00 |