TTC39C Antibody (G-6): sc-390575
- TTC39C Antibody (G-6) is a mouse monoclonal IgG1 κ TTC39C antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 543-571 near the C-terminus of TTC39C of human origin
- TTC39C Antibody (G-6) is recommended for detection of TTC39C of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-TTC39C Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TTC39C Antibody (G-6) for WB applications. These reagents are now offered in bundles with TTC39C Antibody (G-6) (see ordering information below).
TTC39C Antibody (G-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects TTC39C in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TTC39C Antibody (G-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TTC39C plays a crucial role in cellular processes, particularly in regulating cellular iron homeostasis and responding to oxidative stress, which is vital for maintaining cellular health and preventing damage from reactive oxygen species. Dysregulation of iron metabolism can lead to various diseases, including neurodegenerative disorders and cancer, highlighting the importance of studying TTC39C in understanding these conditions. Additionally, chromosome 18, which encodes over 300 genes, is associated with several genetic disorders, including Edwards syndrome, and is implicated in various cancers due to translocations. The TGFβ signaling pathway, which is influenced by proteins encoded on chromosome 18, further underscores TTC39C′s significance in cellular signaling and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TTC39C Antibody (G-6) References:
- Characterisation of a 19-year-old 'long-term survivor' with Edwards syndrome. | Petek, E., et al. 2003. Genet Couns. 14: 239-44. PMID: 12872820
- A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex. | Raghavan, SC., et al. 2004. Nature. 428: 88-93. PMID: 14999286
- Chromosome 18 aberrations and epilepsy: a review. | Grosso, S., et al. 2005. Am J Med Genet A. 134A: 88-94. PMID: 15690352
- Heterogeneity of mutations in the ferrochelatase gene in Italian patients with erythropoietic protoporphyria. | Aurizi, C., et al. 2007. Mol Genet Metab. 90: 402-7. PMID: 17196862
- A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. | Broderick, P., et al. 2007. Nat Genet. 39: 1315-7. PMID: 17934461
- Hereditary hemorrhagic telangiectasia. | Kamal, AH. and Prakash, UB. 2007. Mayo Clin Proc. 82: 1364. PMID: 17976356
- Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism. | Shovlin, CL., et al. 2007. Thromb Haemost. 98: 1031-9. PMID: 18000608
- Linkage of Niemann-Pick disease type C to human chromosome 18. | Carstea, ED., et al. 1993. Proc Natl Acad Sci U S A. 90: 2002-4. PMID: 8446622
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TTC39C Antibody (G-6) | sc-390575 | 200 µg/ml | $322.00 | |||
TTC39C Antibody (G-6): m-IgG Fc BP-HRP Bundle | sc-530193 | 200 µg Ab; 10 µg BP | $361.00 | |||
TTC39C Antibody (G-6): m-IgGκ BP-HRP Bundle | sc-523587 | 200 µg Ab, 40 µg BP | $361.00 | |||
TTC39C Antibody (G-6): m-IgG1 BP-HRP Bundle | sc-543919 | 200 µg Ab; 20 µg BP | $361.00 | |||
TTC39C Antibody (G-6) AC | sc-390575 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TTC39C Antibody (G-6) HRP | sc-390575 HRP | 200 µg/ml | $322.00 | |||
TTC39C Antibody (G-6) FITC | sc-390575 FITC | 200 µg/ml | $336.00 | |||
TTC39C Antibody (G-6) PE | sc-390575 PE | 200 µg/ml | $349.00 | |||
TTC39C Antibody (G-6) Alexa Fluor® 488 | sc-390575 AF488 | 200 µg/ml | $364.00 | |||
TTC39C Antibody (G-6) Alexa Fluor® 546 | sc-390575 AF546 | 200 µg/ml | $364.00 | |||
TTC39C Antibody (G-6) Alexa Fluor® 594 | sc-390575 AF594 | 200 µg/ml | $364.00 | |||
TTC39C Antibody (G-6) Alexa Fluor® 647 | sc-390575 AF647 | 200 µg/ml | $364.00 | |||
TTC39C Antibody (G-6) Alexa Fluor® 680 | sc-390575 AF680 | 200 µg/ml | $364.00 | |||
TTC39C Antibody (G-6) Alexa Fluor® 790 | sc-390575 AF790 | 200 µg/ml | $364.00 | |||
TTC39C (G-6) Neutralizing Peptide | sc-390575 P | 100 µg/0.5 ml | $69.00 |