TRP1 Antibody (B-2): sc-514900
- TRP1 Antibody (B-2) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 30-54 near the N-terminus of TRP1 of mouse origin
- recommended for detection of TRP1 of mouse origin by WB, IP, IF and ELISA
- See TRP1 (G-9): sc-166857 for TRP1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for TRP1 Antibody (B-2) for WB applications. These reagents are now offered in bundles with TRP1 Antibody (B-2) (see ordering information below).
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TRP1 Antibody (B-2) is a mouse monoclonal IgG2b antibody that detects TRP1 in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TRP1, or tyrosinase-related protein 1, plays a crucial role in the melanin biosynthesis pathway, specifically in the production of eumelanin, which is essential for pigmentation in hair, skin, and eyes. TRP1 is primarily located in the melanosomes of melanocytes, where TRP1 works in concert with other enzymes, including tyrosinase and TRP2, to facilitate the conversion of tyrosine to melanin. Proper localization of TRP1 within the melanosomal membrane is vital, as such positioning ensures efficient interaction with its substrate and other melanin-synthesizing enzymes, thereby influencing the overall pigmentation process. Mutations or deficiencies in TRP1 can lead to pigmentation disorders, highlighting TRP1′s importance in maintaining normal skin and hair color. Anti-TRP1 antibody (B-2) serves as an invaluable tool for researchers studying melanin synthesis and related disorders, providing insights into the molecular mechanisms underlying pigmentation and potential therapeutic targets.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRP1 Antibody (B-2) | sc-514900 | 200 µg/ml | $322.00 | |||
TRP1 Antibody (B-2): m-IgG Fc BP-HRP Bundle | sc-541008 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRP1 Antibody (B-2): m-IgG2b BP-HRP Bundle | sc-549798 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRP1 (B-2) Neutralizing Peptide | sc-514900 P | 100 µg/0.5 ml | $69.00 |