Troponin I-FS Antibody (E-1): sc-514969

Troponin I-FS Antibody (E-1) is a mouse monoclonal IgG2a antibody that detects Troponin I in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Troponin I plays a critical role in muscle contraction by regulating the interaction between actin and myosin, which is essential for various cellular movements, including muscle contraction and relaxation. Troponin I is part of the troponin complex, which also includes Troponin C and Troponin T, and is specifically responsible for inhibiting actin-myosin interactions in the absence of calcium. The presence of calcium ions leads to a conformational change in Troponin I, allowing for muscle contraction to occur. Understanding the function of Troponin I is vital, as alterations in Troponin I expression or function can indicate cardiac and skeletal muscle diseases, making Troponin I a key biomarker in clinical diagnostics. Anti-Troponin I antibody (E-1) serves as an invaluable tool for researchers studying muscle physiology and pathophysiology, providing insights into the mechanisms of muscle contraction and the potential for therapeutic interventions.

The preferred Troponin I-FS antibody is Troponin I-FS Antibody (C-11): sc-377451.