Troponin C slow skeletal/cardiac Antibody (7B9): sc-52265

Troponin C slow skeletal/cardiac Antibody (7B9) is a mouse monoclonal IgG1 kappa light chain antibody that detects Troponin C slow skeletal/cardiac protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). Anti-Troponin C slow skeletal/cardiac antibody (7B9) is available as the non-conjugated format. Troponin C slow skeletal/cardiac (7B9) antibody plays a critical role in muscle contraction by binding calcium ions, which induces conformational changes that facilitate the interaction between actin and myosin, the two primary proteins responsible for muscle contraction. This interaction is essential for various physiological processes, including heartbeats and skeletal muscle movements, making Troponin C slow skeletal/cardiac protein a vital component in muscle function regulation. Troponin C slow skeletal/cardiac protein exists in two isoforms, fast and slow, with the slow isoform being particularly important in cardiac muscle, where Troponin C slow skeletal/cardiac protein helps modulate the contractile response to calcium levels. A unique structure characterized by a dumbbell shape and hydrophobic pocket allows Troponin C slow skeletal/cardiac protein to effectively bind calcium, thereby enhancing muscle fiber contractile force. Understanding Troponin C slow skeletal/cardiac protein function and dynamics is crucial for elucidating mechanisms underlying muscle physiology and pathophysiology, particularly in conditions such as heart disease and muscle disorders.

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Troponin C slow skeletal/cardiac Antibody (7B9) References:

1. Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction.  |  Labugger, R., et al. 2000. Circulation. 102: 1221-6. PMID: 10982534
2. Acute coronary syndromes. The diagnostic role of troponins.  |  Hamm, CW. 2001. Thromb Res. 103 Suppl 1: S63-9. PMID: 11567671
3. Cardiac troponins.  |  Sarko, J. and Pollack, CV. 2002. J Emerg Med. 23: 57-65. PMID: 12217473
4. The role of troponins in muscle contraction.  |  Gomes, AV., et al. 2002. IUBMB Life. 54: 323-33. PMID: 12665242
5. Kinetics of cardiac thin-filament activation probed by fluorescence polarization of rhodamine-labeled troponin C in skinned guinea pig trabeculae.  |  Bell, MG., et al. 2006. Biophys J. 90: 531-43. PMID: 16258047
6. [Pathology of the nervous system and pregnancy].  |  Gusev, VA. 1977. Klin Med (Mosk). 55: 16-23. PMID: 926731
7. Characterization of cardiac troponin subunit release into serum after acute myocardial infarction and comparison of assays for troponin T and I. American Association for Clinical Chemistry Subcommittee on cTnI Standardization.  |  Wu, AH., et al. 1998. Clin Chem. 44: 1198-208. PMID: 9625043

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Troponin C slow skeletal/cardiac Antibody (7B9) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-Troponin C slow skeletal/cardiac Antibody (7B9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Troponin C slow skeletal/cardiac Antibody (7B9) Specifications

Alternate Product Name: TNNC1

Product Clone Name: 7B9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: cardiac Troponin C

Epitope Species: human

Product Reactivity/Detection: Troponin C slow skeletal/cardiac

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for Troponin C slow skeletal/cardiac Antibody (7B9): N/A

The preferred Troponin C fast skeletal antibody is Troponin C fast skeletal Antibody (E-7): sc-48347.