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Tropomodulin 3 Antibody (E-3) is a mouse monoclonal IgG2b antibody that detects tropomodulin 3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Tropomodulin 3 plays a crucial role in the regulation of actin filament dynamics by capping the pointed ends of actin filaments, thereby preventing their elongation and depolymerization, which is essential for maintaining cellular structure and function. Anti-tropomodulin 3 antibody (E-3) is particularly important in muscle and neuronal tissues, where tropomodulin 3 contributes to the stability of the cytoskeleton, facilitating proper cellular signaling and mechanical support. The expression of tropomodulin 3 is ubiquitous, with multiple transcripts identified, indicating its vital role across various tissues. The human TMOD3 gene, located on chromosome 15q21.2, encodes a 352 amino acid protein and is associated with the gene for amyotrophic lateral sclerosis 5 (ALS5), highlighting its potential implications in neurodegenerative diseases. Tropomodulin 3 (E-3) antibody is an invaluable tool for researchers studying the dynamics of the cytoskeleton and its impact on cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
tropomodulin 3 Antibody (E-3) | sc-166287 | 200 µg/ml | $322.00 | |||
tropomodulin 3 Antibody (E-3): m-IgG Fc BP-HRP Bundle | sc-537470 | 200 µg Ab; 10 µg BP | $361.00 | |||
tropomodulin 3 Antibody (E-3): m-IgGκ BP-HRP Bundle | sc-534748 | 200 µg Ab; 40 µg BP | $361.00 | |||
tropomodulin 3 (E-3) Neutralizing Peptide | sc-166287 P | 100 µg/0.5 ml | $69.00 |