TRMT1 Antibody (F-8): sc-514876
- TRMT1 Antibody (F-8) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 221-246 within an internal region of TRMT1 of human origin
- recommended for detection of TRMT1 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TRMT1 Antibody (F-8) for WB applications. These reagents are now offered in bundles with TRMT1 Antibody (F-8) (see ordering information below).
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TRMT1 Antibody (F-8) is a mouse monoclonal IgG1 antibody that detects TRMT1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TRMT1, also known as N(2),N(2)-dimethylguanosine tRNA methyltransferase, plays a crucial role in the modification of transfer RNA (tRNA), specifically by dimethylating a guanine residue at position 26, which is essential for maintaining the accuracy of mRNA translation. This modification helps regulate the efficiency of protein synthesis by ensuring that the ribosome reads the mRNA correctly, thereby preventing translational errors that could lead to dysfunctional proteins. TRMT1 consists of 659 amino acids and is primarily located in the nucleus, where TRMT1 is involved in the processing and modification of tRNA molecules. Notably, TRMT1 has two isoforms generated through alternative splicing, and TRMT1 gene is located on chromosome 19p13.13. Mutations in the TRMT1 gene can result in reduced enzyme activity and lower protein levels, which may have implications for cellular function and overall organismal health. anti-TRMT1 antibody (F-8) is an invaluable tool for researchers studying tRNA modifications and their impact on gene expression and protein synthesis.
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Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.
Download thiomersal SDS
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRMT1 Antibody (F-8) | sc-514876 | 200 µg/ml | $322.00 | |||
TRMT1 Antibody (F-8): m-IgG Fc BP-HRP Bundle | sc-541002 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRMT1 Antibody (F-8): m-IgG1 BP-HRP Bundle | sc-542523 | 200 µg Ab; 20 µg BP | $361.00 | |||
TRMT1 (F-8) Neutralizing Peptide | sc-514876 P | 100 µg/0.5 ml | $69.00 |