TRIM23 Antibody (C-1): sc-393923
- TRIM23 Antibody (C-1) is a mouse monoclonal IgG2a κ TRIM23 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of TRIM23 of human origin
- TRIM23 Antibody (C-1) is recommended for detection of TRIM23 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TRIM23 Antibody (C-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for TRIM23 Antibody (C-1) for WB applications. These reagents are now offered in bundles with TRIM23 Antibody (C-1) (see ordering information below).
TRIM23 Antibody (C-1) is a mouse monoclonal IgG2a kappa light chain antibody that detects TRIM23 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TRIM23 Antibody (C-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TRIM23, also known as tripartite motif-containing protein 23, is a 574 amino acid intracytoplasmic membrane protein that plays a crucial role in intracellular transport processes. TRIM23 is primarily located in the Golgi apparatus and lysosomal structures, where TRIM23 is involved in the formation and movement of transport vesicles between cellular compartments. This localization is vital for maintaining cellular homeostasis and facilitating the trafficking of proteins and lipids, which are essential for various cellular functions. Additionally, TRIM23 is part of the TRIM protein family and the ADP ribosylation factor family of guanine nucleotide-binding proteins, and TRIM23 interacts with cytohesin-1, a relationship that enhances TRIM23′s functional capabilities. Notably, TRIM23 has three isoforms—alpha, beta, and gamma—resulting from alternative splicing, which may contribute to diverse biological roles.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TRIM23 Antibody (C-1) References:
- Specific functional interaction of human cytohesin-1 and ADP-ribosylation factor domain protein (ARD1). | Vitale, N., et al. 2000. J Biol Chem. 275: 21331-9. PMID: 10748148
- Control of hnRNP A1 alternative splicing: an intron element represses use of the common 3' splice site. | Simard, MJ. and Chabot, B. 2000. Mol Cell Biol. 20: 7353-62. PMID: 10982852
- E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1). | Vichi, A., et al. 2005. Proc Natl Acad Sci U S A. 102: 1945-50. PMID: 15684077
- ADP-ribosylation factor domain protein 1 (ARD1), a multifunctional protein with ubiquitin E3 ligase, GAP, and ARF domains. | Vichi, A., et al. 2005. Methods Enzymol. 404: 195-206. PMID: 16413270
- ARD 1, a 64-kDa guanine nucleotide-binding protein with a carboxyl-terminal ADP-ribosylation factor domain. | Mishima, K., et al. 1993. J Biol Chem. 268: 8801-7. PMID: 8473324
- Localization of ADP-ribosylation factor domain protein 1 (ARD1) in lysosomes and Golgi apparatus. | Vitale, N., et al. 1998. Proc Natl Acad Sci U S A. 95: 8613-8. PMID: 9671726
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRIM23 Antibody (C-1) | sc-393923 | 200 µg/ml | $322.00 | |||
TRIM23 Antibody (C-1): m-IgG Fc BP-HRP Bundle | sc-526274 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRIM23 Antibody (C-1): m-IgG2a BP-HRP Bundle | sc-546554 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRIM23 Antibody (C-1) AC | sc-393923 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TRIM23 Antibody (C-1) HRP | sc-393923 HRP | 200 µg/ml | $322.00 | |||
TRIM23 Antibody (C-1) FITC | sc-393923 FITC | 200 µg/ml | $336.00 | |||
TRIM23 Antibody (C-1) PE | sc-393923 PE | 200 µg/ml | $349.00 | |||
TRIM23 Antibody (C-1) Alexa Fluor® 488 | sc-393923 AF488 | 200 µg/ml | $364.00 | |||
TRIM23 Antibody (C-1) Alexa Fluor® 546 | sc-393923 AF546 | 200 µg/ml | $364.00 | |||
TRIM23 Antibody (C-1) Alexa Fluor® 594 | sc-393923 AF594 | 200 µg/ml | $364.00 | |||
TRIM23 Antibody (C-1) Alexa Fluor® 647 | sc-393923 AF647 | 200 µg/ml | $364.00 | |||
TRIM23 Antibody (C-1) Alexa Fluor® 680 | sc-393923 AF680 | 200 µg/ml | $364.00 | |||
TRIM23 Antibody (C-1) Alexa Fluor® 790 | sc-393923 AF790 | 200 µg/ml | $364.00 |