

TRAF4 Antibody (D-2) is a mouse monoclonal IgG1 antibody that detects TRAF4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TRAF4, originally known as CART1, plays a crucial role in the signaling pathways of the tumor necrosis factor receptor superfamily, particularly in breast carcinomas where TRAF4 is specifically expressed. TRAF4 is primarily localized in the nucleus of these tissues, suggesting a role in regulating gene expression and cellular responses to external stimuli. Nuclear localization of TRAF4 is essential for mediating the activation of transcription factors such as NFkB, which are pivotal in controlling inflammation and immune responses. Furthermore, TRAF4 interacts with various signaling molecules, including members of the TRAF family, which are critical for transducing signals from TNF receptors and other related receptors. TRAF4′s ability to modulate these pathways highlights TRAF4′s importance in both normal cellular functions and pathological conditions, making anti-TRAF4 antibody (D-2) a valuable tool for researchers studying these complex signaling networks.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRAF4 Antibody (D-2) | sc-390212 | 200 µg/ml | $322.00 | |||
TRAF4 Antibody (D-2): m-IgG Fc BP-HRP Bundle | sc-540769 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRAF4 Antibody (D-2): m-IgG1 BP-HRP Bundle | sc-542361 | 200 µg Ab; 20 µg BP | $361.00 | |||
TRAF4 (D-2) Neutralizing Peptide | sc-390212 P | 100 µg/0.5 ml | $69.00 |