Anti-Tra-2β Antibody (D-2) is a mouse monoclonal IgG2a κ Tra-2β antibody, cited in 3 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 19-36 near the N-terminus of Tra-2β of human origin
Anti-Tra-2 beta Antibody (D-2) is recommended for detection of Tra-2β of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-Tra-2 beta Antibody (D-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for ChIP application (sc-166829 X, 200 µg/0.1 ml)
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Tra-2β (D-2): sc-166829.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for Tra-2β Antibody (D-2) for WB and IHC(P) applications. These reagents are now offered in bundles with Tra-2β Antibody (D-2) (see ordering information below).
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Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Tra-2β Antibody (D-2) is a high quality monoclonal Tra-2 beta antibody (also designated Tra-2β antibody) suitable for the detection of the Tra-2 beta protein of mouse, rat and human origin. Tra-2β Antibody (D-2) is available as both the non-conjugated anti-Tra-2 beta antibody form, as well as multiple conjugated forms of anti-Tra-2 beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Human transformer-2 alpha (Tra-2α) and Tra-2β are nuclear proteins that associate with distinct pre-mRNA splicing enhancer elements. Tra-2α is the functional homolog of the Drosophila TRA-2 protein, which regulates the female specific pre-mRNA splicing pattern of the doublesex (dsx) gene in Drosophila. Human Tra-2 proteins are able to actively splice Drosophila sex factors; however, human Tra-2α has not been shown to induce sexual differentiation suggesting that human Tra-2α may regulate splicing patterns involving alternative mechanisms. Tra-2α and Tra-2β contain a single RNP-type RNA-binding domain and selectively bind to purine-rich sequences to facilitate mRNA splicing. Expression of Tra-2β is upregulated during the reoxygenation of hypoxic astrocytes. Tra-2α and Tra-2β interact with the serine/arginine-rich (SR) family of splicing factors to form Tra-2/SR complexes that then regulate tissue-specific alternative splicing patterns of many pre-mRNAs.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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