TNFα-IP 1 Antibody (F-4): sc-515765
- TNFα-IP 1 Antibody (F-4) is a mouse monoclonal IgG1 κ TNFα-IP 1 antibody, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 253-316 mapping at the C-terminus of TNFα-IP 1 of human origin
- TNF alpha-IP 1 Antibody (F-4) is recommended for detection of TNFα-IP 1 of human origin by WB, IP, IF and ELISA
- Anti-TNF alpha-IP 1 Antibody (F-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TNFα-IP 1 Antibody (F-4) for WB applications. These reagents are now offered in bundles with TNFα-IP 1 Antibody (F-4) (see ordering information below).
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TNFα-IP 1 Antibody (F-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects TNFα-IP 1 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TNFα-IP 1 (F-4) antibody is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TNFα-IP 1, also known as tumor necrosis factor, alpha-induced protein 1, endothelial, or by alternative names B12, B61, and EDP1, is a member of the BTB/POZ domain-containing protein family, specifically the KCTD10/KCTD13/TNFAIP1 group. TNFα-IP 1 plays a crucial role in cellular processes such as DNA repair and apoptosis, which are vital for maintaining genomic stability and regulating cell death. A BTB/POZ motif in TNFα-IP 1 facilitates interactions essential for transcriptional regulation and chromatin remodeling, thereby influencing gene expression in response to cellular stressors. TNFα-IP 1 expression can be induced by interleukin-6 and tumor necrosis factor alpha in endothelial cells, linking TNFα-IP 1 to inflammatory responses and potential implications in cancer progression and innate immunity against viral infections, such as Hepatitis B.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TNFα-IP 1 Antibody (F-4) References:
- Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model. | Link, CD., et al. 2003. Neurobiol Aging. 24: 397-413. PMID: 12600716
- Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigen. | Zhou, J., et al. 2005. J Exp Zool A Comp Exp Biol. 303: 227-40. PMID: 15726626
- Tumor necrosis factor-alpha-induced protein 1 and immunity to hepatitis B virus. | Lin, MC., et al. 2005. World J Gastroenterol. 11: 7564-8. PMID: 16437679
- [Expression profile in the cell lines of human TNFAIP1 gene]. | Yang, LP., et al. 2006. Yi Chuan. 28: 918-22. PMID: 16870576
- Role of inflammatory mediators in the suppression of insulin receptor phosphorylation in circulating mononuclear cells of obese subjects. | Ghanim, H., et al. 2007. Diabetologia. 50: 278-85. PMID: 17180352
- Comparative analysis of transcriptional profiling of CD3+, CD4+ and CD8+ T cells identifies novel immune response players in T-cell activation. | Wang, M., et al. 2008. BMC Genomics. 9: 225. PMID: 18485203
- The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation. | Ding, X., et al. 2009. J Cell Biochem. 106: 285-95. PMID: 19115315
- Structure and chromosomal mapping of the TNF-alpha inducible endothelial protein 1 (Edp1) gene in the mouse. | Swift, S., et al. 1998. Biochim Biophys Acta. 1442: 394-8. PMID: 9804998
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNFα-IP 1 Antibody (F-4) | sc-515765 | 200 µg/ml | $322.00 | |||
TNFα-IP 1 Antibody (F-4): m-IgG Fc BP-HRP Bundle | sc-531507 | 200 µg Ab; 10 µg BP | $361.00 | |||
TNFα-IP 1 Antibody (F-4): m-IgGκ BP-HRP Bundle | sc-525207 | 200 µg Ab, 40 µg BP | $361.00 | |||
TNFα-IP 1 Antibody (F-4): m-IgG1 BP-HRP Bundle | sc-544598 | 200 µg Ab; 20 µg BP | $361.00 | |||
TNFα-IP 1 Antibody (F-4) AC | sc-515765 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TNFα-IP 1 Antibody (F-4) HRP | sc-515765 HRP | 200 µg/ml | $322.00 | |||
TNFα-IP 1 Antibody (F-4) FITC | sc-515765 FITC | 200 µg/ml | $336.00 | |||
TNFα-IP 1 Antibody (F-4) PE | sc-515765 PE | 200 µg/ml | $349.00 | |||
TNFα-IP 1 Antibody (F-4) Alexa Fluor® 488 | sc-515765 AF488 | 200 µg/ml | $364.00 | |||
TNFα-IP 1 Antibody (F-4) Alexa Fluor® 546 | sc-515765 AF546 | 200 µg/ml | $364.00 | |||
TNFα-IP 1 Antibody (F-4) Alexa Fluor® 594 | sc-515765 AF594 | 200 µg/ml | $364.00 | |||
TNFα-IP 1 Antibody (F-4) Alexa Fluor® 647 | sc-515765 AF647 | 200 µg/ml | $364.00 | |||
TNFα-IP 1 Antibody (F-4) Alexa Fluor® 680 | sc-515765 AF680 | 200 µg/ml | $364.00 | |||
TNFα-IP 1 Antibody (F-4) Alexa Fluor® 790 | sc-515765 AF790 | 200 µg/ml | $364.00 |