TNFβ Antibody (359-81-11): sc-32767
- TNFβ Antibody (359-81-11) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant TNFβ of human origin
- recommended for detection of TNFβ of human origin by WB, IP and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for neutralizing, sc-32767 L, 200 µg/0.1 ml
- m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TNFβ Antibody (359-81-11) for WB applications. These reagents are now offered in bundles with TNFβ Antibody (359-81-11) (see ordering information below).
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TNFβ Antibody (359-81-11) is a mouse monoclonal IgG1 antibody that detects tumor necrosis factor beta (TNFβ) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). TNFβ is a pleiotropic cytokine primarily produced by activated lymphocytes, including CD4(+) T helper type 1 cells, CD8(+) lymphocytes, and certain B lymphoblastoid cell lines, playing a crucial role in immune regulation and inflammation. TNFβ monoclonal antibody (359-81-11) helps researchers study this protein′s ability to modulate various immune responses and inhibit tumor growth, making TNFβ a significant target for therapeutic interventions in cancer and autoimmune diseases. Notably, TNFβ interacts with TNF receptors 1 and 2 on target tumor cells, with the p55 receptor being particularly critical for mediating the cytotoxic response. Understanding the interactions and signaling pathways involving TNFβ is essential for developing strategies to enhance therapeutic efficacy and mitigate adverse effects in clinical settings. Anti-TNFβ antibody (359-81-11) serves as an invaluable tool for researchers investigating the complex roles of this cytokine in health and disease.
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TNFβ Antibody (359-81-11) References:
- Tumor necrosis factor beta and ultraviolet radiation are potent regulators of human keratinocyte ICAM-1 expression. | Krutmann, J., et al. 1990. J Invest Dermatol. 95: 127-31. PMID: 1974275
- Tumor necrosis factor-beta in the serum of adult T-cell leukemia with hypercalcemia. | Ishibashi, K., et al. 1991. Blood. 77: 2451-5. PMID: 2039827
- Association of tumor necrosis factor β genetic polymorphism and sepsis susceptibility. | Delongui, F., et al. 2011. Exp Ther Med. 2: 349-356. PMID: 22977509
- Association between the G252A Tumor Necrosis Factor-β Gene Polymorphism and Medication-Overuse Headache. | Ishii, M., et al. 2012. J Clin Neurol. 8: 301-4. PMID: 23323139
- Association between tumor necrosis factor β 252 A/G polymorphism and risk of gastric cancer: a meta-analysis. | Xu, Z., et al. 2013. Tumour Biol. 34: 4001-5. PMID: 23904263
- Tumor necrosis factor-β Nco1 polymorphism and susceptibility to sepsis following major elective surgery. | Baghel, K., et al. 2014. Surg Infect (Larchmt). 15: 213-20. PMID: 24796628
- Effects of tumor necrosis factor-β (TNF-β) 252A>G polymorphism on the development of migraine: a meta-analysis. | Liu, R., et al. 2014. PLoS One. 9: e100189. PMID: 24959879
- Tumor necrosis factor beta NcoI polymorphism is associated with inflammatory and metabolic markers in multiple sclerosis patients. | Kallaur, AP., et al. 2014. J Neurol Sci. 346: 156-63. PMID: 25173940
- Higher levels of tumor necrosis factor β are associated with frailty in socially vulnerable community-dwelling older adults. | Nascimento, CMC., et al. 2018. BMC Geriatr. 18: 268. PMID: 30400833
- Down-regulation of human tumor necrosis factor-beta gene expression by cells with suppressive activity. | Aframian, D., et al. 1996. Immunol Lett. 54: 171-6. PMID: 9052873
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNFβ Antibody (359-81-11) | sc-32767 | 200 µg/ml | $322.00 | |||
TNFβ Antibody (359-81-11): m-IgGκ BP-HRP Bundle | sc-533908 | 200 µg Ab; 40 µg BP | $361.00 | |||
TNFβ Antibody (359-81-11): m-IgG1 BP-HRP Bundle | sc-538853 | 200 µg Ab; 20 µg BP | $361.00 | |||
TNFβ Antibody (359-81-11) FITC | sc-32767 FITC | 200 µg/ml | $336.00 | |||
TNFβ Antibody (359-81-11) L | sc-32767 L | 200 µg/0.1 ml | $322.00 | |||
TNFβ Antibody (359-81-11) PE | sc-32767 PE | 200 µg/ml | $349.00 |