TNF alpha Antibody (E7D2): sc-101425
- TNF alpha Antibody (E7D2) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant TNFα of human origin
- recommended for detection of TNFα of human origin by WB and ELISA
- See TNF alpha (C-4): sc-133192 for TNF alpha antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TNF alpha Antibody (E7D2) for WB applications. These reagents are now offered in bundles with TNF alpha Antibody (E7D2) (see ordering information below).
TNFα Antibody (E7D2) is a mouse monoclonal IgG1 antibody that detects tumor necrosis factor α (TNFα) in human samples through applications such as western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). TNFα is a critical cytokine involved in systemic inflammation and is produced by various immune cells, including lymphocytes, neutrophils, and macrophages. Anti-TNFα antibody (E7D2) plays a vital role in studying immune responses by detecting TNFα′s regulation of other immune cells and promotion of inflammatory processes, which are essential for fighting infections and healing injuries. Dysregulation of TNFα can lead to chronic inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease, highlighting TNFα′s importance in both health and disease. TNFα monoclonal antibody (E7D2) provides reliable detection of this key cytokine, facilitating research into TNFα′s functions and interactions in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TNF alpha Antibody (E7D2) References:
- Changing paradigms in dermatology: tumor necrosis factor alpha (TNF-alpha) blockade in psoriasis and psoriatic arthritis. | Victor, FC., et al. 2003. Clin Dermatol. 21: 392-7. PMID: 14678719
- Liver diseases associated with anti-tumor necrosis factor-alpha (TNF-α) use for inflammatory bowel disease. | Coffin, CS., et al. 2011. Inflamm Bowel Dis. 17: 479-84. PMID: 20848520
- Modulation of anti-tumor necrosis factor alpha (TNF-α) antibody secretion in mice immunized with TNF-α kinoid. | Assier, E., et al. 2012. Clin Vaccine Immunol. 19: 699-703. PMID: 22441388
- Central Leptin and Tumor Necrosis Factor-α (TNFα) in Diurnal Control of Blood Pressure and Hypertension. | Han, C., et al. 2016. J Biol Chem. 291: 15131-42. PMID: 27226618
- Bacteriophage-mediated therapy of chondrosarcoma by selective delivery of the tumor necrosis factor alpha (TNFα) gene. | Chongchai, A., et al. 2021. FASEB J. 35: e21487. PMID: 33811705
- Butorphanol tartrate mitigates cellular senescence against tumor necrosis factor -α (TNF-α) in human HC-A chondrocytes. | Zhang, C., et al. 2022. Bioengineered. 13: 5434-5442. PMID: 35184641
- Tumor Necrosis Factor-α (TNFα) Stimulate Triple-Negative Breast Cancer Stem Cells to Promote Intratumoral Invasion and Neovasculogenesis in the Liver of a Xenograft Model. | Narasimhan, H., et al. 2022. Biology (Basel). 11: PMID: 36290384
- Neutrophil gelatinase-associated lipocalin (NGAL) and tumor necrosis factor-α (TNF-α) levels in patients with schizophrenia. | Gül Çakıl, A., et al. 2023. Psychopharmacology (Berl). 240: 1091-1101. PMID: 36877232
- Association of Tumor Necrosis Factor-Alpha (TNF-α) rs1800629 Polymorphism in Chronic Kidney Disease. | Lanka, S., et al. 2024. Cureus. 16: e60332. PMID: 38883059
- Tumor necrosis factor alpha (TNF-alpha) gene therapy targeted by ionizing radiation selectively damages tumor vasculature. | Mauceri, HJ., et al. 1996. Cancer Res. 56: 4311-4. PMID: 8813113
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TNF alpha Antibody (E7D2) | sc-101425 | 200 µg/ml | $322.00 | |||
TNF alpha Antibody (E7D2): m-IgG Fc BP-HRP Bundle | sc-539761 | 200 µg Ab; 10 µg BP | $361.00 | |||
TNF alpha Antibody (E7D2): m-IgG1 BP-HRP Bundle | sc-541691 | 200 µg Ab; 20 µg BP | $361.00 |