TMP21 Antibody (F-9): sc-137002
- TMP21 Antibody (F-9) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 41-105 mapping near the N-terminus of TMP21 of human origin
- recommended for detection of TMP21 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TMP21 Antibody (F-9) for WB and IHC(P) applications. These reagents are now offered in bundles with TMP21 Antibody (F-9) (see ordering information below).
QUICK LINKS
TMP21 Antibody (F-9) is a mouse monoclonal IgG2a antibody that detects TMP21 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TMP21, also known as TMED10, is a crucial member of the EMP24/GP25L/p24 cargo family, playing a vital role in regulating vesicular trafficking within the early secretory pathway. TMP21 is predominantly located in the Golgi cisternae and plasma membrane, where TMP21 functions as a single-pass type I membrane protein. TMP21′s localization facilitates transport and quality control of proteins between the endoplasmic reticulum and Golgi complex, ensuring only properly folded and assembled proteins proceed through the secretory pathway. TMP21 is an integral component of the heteromeric secretase complex, which is essential for regulating γ-secretase activity, a process that has implications in various cellular functions and diseases, including Alzheimer′s disease. Anti-TMP21 antibody (F-9) recognizes both TMP21-I and TMP21-II isoforms, providing versatility for researchers studying this important protein in different biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMP21 Antibody (F-9) | sc-137002 | 200 µg/ml | $322.00 | |||
TMP21 Antibody (F-9): m-IgG Fc BP-HRP Bundle | sc-537387 | 200 µg Ab; 10 µg BP | $361.00 | |||
TMP21 Antibody (F-9): m-IgGκ BP-HRP Bundle | sc-534638 | 200 µg Ab; 40 µg BP | $361.00 | |||
TMP21 Antibody (F-9): m-IgG2a BP-HRP Bundle | sc-548001 | 200 µg Ab; 10 µg BP | $361.00 |