TMEM86A Antibody (F-1): sc-390329
- TMEM86A Antibody (F-1) is a mouse monoclonal IgG2a κ TMEM86A antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 228-240 at the C-terminus of TMEM86A of human origin
- TMEM86A Antibody (F-1) is recommended for detection of TMEM86A of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-TMEM86A Antibody (F-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TMEM86A Antibody (F-1) for WB and IHC(P) applications. These reagents are now offered in bundles with TMEM86A Antibody (F-1) (see ordering information below).
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TMEM86A Antibody (F-1) is a mouse monoclonal IgG2a kappa light chain antibody that detects TMEM86A protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-TMEM86A antibody (F-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TMEM86A protein, also known as transmembrane protein 86A, consists of 220 amino acids and is encoded by a gene located on human chromosome 11, a region known for its high density of gene and disease associations. TMEM86A protein is primarily localized in the endoplasmic reticulum and plays a crucial role in cellular signaling and membrane dynamics, which are essential for maintaining cellular homeostasis and responding to environmental stimuli. Understanding TMEM86A function and localization is vital, as disruptions in TMEM86A activity may contribute to various pathophysiological conditions, including neurodegenerative diseases and cancer. TMEM86A monoclonal antibody (F-1) is an invaluable tool for researchers investigating the biological significance of TMEM86A protein in human health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TMEM86A Antibody (F-1) References:
- The 11q terminal deletion disorder: a prospective study of 110 cases. | Grossfeld, PD., et al. 2004. Am J Med Genet A. 129A: 51-61. PMID: 15266616
- Human chromosome 11 DNA sequence and analysis including novel gene identification. | Taylor, TD., et al. 2006. Nature. 440: 497-500. PMID: 16554811
- KCNQ1 K+ channel-mediated cardiac channelopathies. | Loussouarn, G., et al. 2006. Methods Mol Biol. 337: 167-83. PMID: 16929947
- Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome. | Zehelein, J., et al. 2006. J Biol Chem. 281: 35397-403. PMID: 16987820
- Beta-thalassaemia and sickle cell anaemia as paradigms of hypercoagulability. | Ataga, KI., et al. 2007. Br J Haematol. 139: 3-13. PMID: 17854302
- The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3. | Berger, AC., et al. 2007. J Cell Sci. 120: 3640-52. PMID: 17895371
- Wilms tumour: prognostic factors, staging, therapy and late effects. | Kaste, SC., et al. 2008. Pediatr Radiol. 38: 2-17. PMID: 18026723
- Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. | Lee, JH. and Paull, TT. 2007. Oncogene. 26: 7741-8. PMID: 18066086
- Targeted cancer therapies based on the inhibition of DNA strand break repair. | O'Connor, MJ., et al. 2007. Oncogene. 26: 7816-24. PMID: 18066095
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMEM86A Antibody (F-1) | sc-390329 | 200 µg/ml | $316.00 | |||
TMEM86A Antibody (F-1): m-IgG Fc BP-HRP Bundle | sc-530128 | 200 µg Ab; 10 µg BP | $354.00 | |||
TMEM86A Antibody (F-1): m-IgGκ BP-HRP Bundle | sc-523493 | 200 µg Ab, 40 µg BP | $354.00 | |||
TMEM86A Antibody (F-1): m-IgG2a BP-HRP Bundle | sc-547440 | 200 µg Ab; 10 µg BP | $354.00 | |||
TMEM86A Antibody (F-1) AC | sc-390329 AC | 500 µg/ml, 25% agarose | $416.00 | |||
TMEM86A Antibody (F-1) HRP | sc-390329 HRP | 200 µg/ml | $316.00 | |||
TMEM86A Antibody (F-1) FITC | sc-390329 FITC | 200 µg/ml | $330.00 | |||
TMEM86A Antibody (F-1) PE | sc-390329 PE | 200 µg/ml | $343.00 | |||
TMEM86A Antibody (F-1) Alexa Fluor® 488 | sc-390329 AF488 | 200 µg/ml | $357.00 | |||
TMEM86A Antibody (F-1) Alexa Fluor® 546 | sc-390329 AF546 | 200 µg/ml | $357.00 | |||
TMEM86A Antibody (F-1) Alexa Fluor® 594 | sc-390329 AF594 | 200 µg/ml | $357.00 | |||
TMEM86A Antibody (F-1) Alexa Fluor® 647 | sc-390329 AF647 | 200 µg/ml | $357.00 | |||
TMEM86A Antibody (F-1) Alexa Fluor® 680 | sc-390329 AF680 | 200 µg/ml | $357.00 | |||
TMEM86A Antibody (F-1) Alexa Fluor® 790 | sc-390329 AF790 | 200 µg/ml | $357.00 | |||
TMEM86A (F-1) Neutralizing Peptide | sc-390329 P | 100 µg/0.5 ml | $68.00 |