TMEM70 Antibody (G-11): sc-393714

TMEM70 Antibody (G-11) is a mouse monoclonal IgG1 antibody that detects TMEM70 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TMEM70 is a crucial multi-pass mitochondrial membrane protein composed of 260 amino acids, existing in various alternatively spliced isoforms predominantly expressed in the pancreas, liver, muscle, and kidney tissues. TMEM70 facilitates ADP-stimulated respiration and mitochondrial ATP synthesis, which are vital for cellular energy production and overall metabolic health. Mutations in the TMEM70 gene have been linked to ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy, underscoring TMEM70′s role in maintaining mitochondrial function and membrane potential. The gene encoding TMEM70 is located on human chromosome 8, a region that spans nearly 146 million base pairs and contains over 800 genes, many of which are implicated in various diseases and malignancies. Anti-TMEM70 antibody (G-11) is an essential tool for researchers investigating mitochondrial dysfunction and related pathologies.

The preferred TMEM70 antibody is TMEM70 Antibody (B-6): sc-393619.