TMEM43 Antibody (F-3): sc-271887
- TMEM43 Antibody (F-3) is a mouse monoclonal IgG1 (lambda light chain) provided at 200 µg/ml
- specific for an epitope mapping between amino acids 239-261 within a cytoplasmic domain of TMEM43 of human origin
- recommended for detection of TMEM43 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and canine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TMEM43 Antibody (F-3) for WB applications. These reagents are now offered in bundles with TMEM43 Antibody (F-3) (see ordering information below).
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SEE ALSO...
TMEM43 Antibody (F-3) is a mouse monoclonal IgG1 antibody that detects TMEM43 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TMEM43, also known as transmembrane protein 43, LUMA, ARVC5, or ARVD5, is a 400 amino acid multi-pass membrane protein predominantly localized to the inner nuclear membrane and the endoplasmic reticulum. This localization is crucial as TMEM43 plays a significant role in maintaining the structural integrity of the nuclear envelope and is essential for the retention of emerin at the nuclear membrane. Proper functioning of TMEM43 is vital for cardiac health, as mutations in the gene encoding TMEM43 are linked to familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), a serious inherited condition that can lead to heart failure and sudden cardiac death. Anti-TMEM43 antibody (F-3) enables researchers to gain insights into TMEM43′s role in cellular processes and implications in cardiac diseases, making this tool invaluable for studies focused on cardiac health and nuclear envelope dynamics.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMEM43 Antibody (F-3) | sc-271887 | 200 µg/ml | $322.00 | |||
TMEM43 Antibody (F-3): m-IgG Fc BP-HRP Bundle | sc-540272 | 200 µg Ab; 10 µg BP | $361.00 | |||
TMEM43 Antibody (F-3): m-IgG1 BP-HRP Bundle | sc-542016 | 200 µg Ab; 20 µg BP | $361.00 | |||
TMEM43 (F-3) Neutralizing Peptide | sc-271887 P | 100 µg/0.5 ml | $69.00 |