TMEM17 Antibody (G-10): sc-514433
- TMEM17 Antibody (G-10) is a mouse monoclonal IgG2a κ TMEM17 antibody, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-17 at the N-terminus of TMEM17 of human origin
- TMEM17 Antibody (G-10) is recommended for detection of TMEM17 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TMEM17 Antibody (G-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TMEM17 Antibody (G-10) for WB applications. These reagents are now offered in bundles with TMEM17 Antibody (G-10) (see ordering information below).
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TMEM17 Antibody (G-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects TMEM17 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TMEM17 (G-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TMEM17 protein, also known as transmembrane protein 17, consists of 198 amino acids and is encoded by a gene located on human chromosome 2, which is notable for its size and number of genes. TMEM17 protein is primarily localized in the endoplasmic reticulum and plays a crucial role in cellular processes such as protein folding and trafficking, which are essential for maintaining cellular homeostasis and function. Disruptions in TMEM17 function can lead to various cellular dysfunctions, highlighting TMEM17′s importance in health and disease. Additionally, TMEM17 has been implicated in interactions with other proteins involved in cellular signaling pathways, further underscoring TMEM17′s significance in cellular biology. Anti-TMEM17 antibody (G-10) effectively detects TMEM17 across multiple species and applications, making this research tool valuable for studying TMEM17′s role in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TMEM17 Antibody (G-10) References:
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. | Hillier, LW., et al. 2005. Nature. 434: 724-31. PMID: 15815621
- Evidence for an ancestral alphoid domain on the long arm of human chromosome 2. | Avarello, R., et al. 1992. Hum Genet. 89: 247-9. PMID: 1587535
- ABCA12 is the major harlequin ichthyosis gene. | Thomas, AC., et al. 2006. J Invest Dermatol. 126: 2408-13. PMID: 16902423
- Regulation of intestinal cholesterol absorption. | Wang, DQ. 2007. Annu Rev Physiol. 69: 221-48. PMID: 17002594
- A two-carbon switch to sterol-induced autophagic death. | Tabas, I. 2007. Autophagy. 3: 38-41. PMID: 17172803
- Spectrum of ALMS1 variants and evaluation of genotype-phenotype correlations in Alström syndrome. | Marshall, JD., et al. 2007. Hum Mutat. 28: 1114-23. PMID: 17594715
- Compound heterozygous ABCA12 mutations including a novel nonsense mutation underlie harlequin ichthyosis. | Akiyama, M., et al. 2007. Dermatology. 215: 155-9. PMID: 17684380
- Alström syndrome. | Marshall, JD., et al. 2007. Eur J Hum Genet. 15: 1193-202. PMID: 17940554
- Origin of human chromosome 2: an ancestral telomere-telomere fusion. | IJdo, JW., et al. 1991. Proc Natl Acad Sci U S A. 88: 9051-5. PMID: 1924367
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMEM17 Antibody (G-10) | sc-514433 | 200 µg/ml | $316.00 | |||
TMEM17 Antibody (G-10): m-IgG Fc BP-HRP Bundle | sc-531125 | 200 µg Ab; 10 µg BP | $354.00 | |||
TMEM17 Antibody (G-10): m-IgGκ BP-HRP Bundle | sc-524724 | 200 µg Ab, 40 µg BP | $354.00 | |||
TMEM17 Antibody (G-10): m-IgG2a BP-HRP Bundle | sc-547694 | 200 µg Ab; 10 µg BP | $354.00 | |||
TMEM17 Antibody (G-10) AC | sc-514433 AC | 500 µg/ml, 25% agarose | $416.00 | |||
TMEM17 Antibody (G-10) HRP | sc-514433 HRP | 200 µg/ml | $316.00 | |||
TMEM17 Antibody (G-10) FITC | sc-514433 FITC | 200 µg/ml | $330.00 | |||
TMEM17 Antibody (G-10) PE | sc-514433 PE | 200 µg/ml | $343.00 | |||
TMEM17 Antibody (G-10) Alexa Fluor® 488 | sc-514433 AF488 | 200 µg/ml | $357.00 | |||
TMEM17 Antibody (G-10) Alexa Fluor® 546 | sc-514433 AF546 | 200 µg/ml | $357.00 | |||
TMEM17 Antibody (G-10) Alexa Fluor® 594 | sc-514433 AF594 | 200 µg/ml | $357.00 | |||
TMEM17 Antibody (G-10) Alexa Fluor® 647 | sc-514433 AF647 | 200 µg/ml | $357.00 | |||
TMEM17 Antibody (G-10) Alexa Fluor® 680 | sc-514433 AF680 | 200 µg/ml | $357.00 | |||
TMEM17 Antibody (G-10) Alexa Fluor® 790 | sc-514433 AF790 | 200 µg/ml | $357.00 | |||
TMEM17 (G-10) Neutralizing Peptide | sc-514433 P | 100 µg/0.5 ml | $68.00 |