TMCC3 Antibody (D-6): sc-515583
- TMCC3 Antibody (D-6) is a mouse monoclonal IgG1 κ TMCC3 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-26 at the N-terminus of TMCC3 of human origin
- TMCC3 Antibody (D-6) is recommended for detection of TMCC3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TMCC3 Antibody (D-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TMCC3 Antibody (D-6) for WB applications. These reagents are now offered in bundles with TMCC3 Antibody (D-6) (see ordering information below).
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TMCC3 Antibody (D-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects TMCC3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TMCC3 (D-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TMCC3, or transmembrane and coiled-coil domains protein 3, is a 477 amino acid multi-pass membrane protein that plays a critical role in cellular processes, particularly in membrane dynamics and protein interactions. Located primarily in the endoplasmic reticulum and Golgi apparatus, TMCC3 is essential for proper trafficking and localization of proteins within the cell, which is vital for maintaining cellular homeostasis and function. Disruptions in TMCC3 function can lead to various cellular dysfunctions, potentially contributing to developmental disorders and diseases. The gene encoding TMCC3 is situated on human chromosome 12q22, a region associated with several genetic conditions, including skeletal deformities and developmental syndromes. Understanding TMCC3 and its interactions within the cellular environment can provide insights into its significance in health and disease, making anti-TMCC3 antibody (D-6) a valuable tool for researchers studying these pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
TMCC3 Antibody (D-6) References:
- [Achondrogenesis type II-hypochondrogenesis: radiological features.Case report]. | Delgado Carrasco, J., et al. 2001. An Esp Pediatr. 55: 553-7. PMID: 11730591
- A case of Kniest dysplasia with retinal detachment and the mutation analysis. | Yokoyama, T., et al. 2003. Am J Ophthalmol. 136: 1186-8. PMID: 14644246
- A familial case of achondrogenesis type II caused by a dominant COL2A1 mutation and 'patchy' expression in the mosaic father. | Forzano, F., et al. 2007. Am J Med Genet A. 143A: 2815-20. PMID: 17994563
- Visceral manifestations of hypochondrogenesis. | Wainwright, H. and Beighton, P. 2008. Virchows Arch. 453: 203-7. PMID: 18642028
- Trisomy 12p and monosomy 4p: phenotype-genotype correlation. | Benussi, DG., et al. 2009. Genet Test Mol Biomarkers. 13: 199-204. PMID: 19378504
- High resolution melting analysis for mutation detection for PTPN11 gene: applications of this method for diagnosis of Noonan syndrome. | Lo, FS., et al. 2009. Clin Chim Acta. 409: 75-7. PMID: 19737548
- Cytogenetic and molecular analysis in trisomy 12p. | Allen, TL., et al. 1996. Am J Med Genet. 63: 250-6. PMID: 8723118
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TMCC3 Antibody (D-6) | sc-515583 | 200 µg/ml | $322.00 | |||
TMCC3 Antibody (D-6): m-IgG Fc BP-HRP Bundle | sc-531427 | 200 µg Ab; 10 µg BP | $361.00 | |||
TMCC3 Antibody (D-6): m-IgGκ BP-HRP Bundle | sc-525115 | 200 µg Ab, 40 µg BP | $361.00 | |||
TMCC3 Antibody (D-6): m-IgG1 BP-HRP Bundle | sc-544548 | 200 µg Ab; 20 µg BP | $361.00 | |||
TMCC3 Antibody (D-6) AC | sc-515583 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TMCC3 Antibody (D-6) HRP | sc-515583 HRP | 200 µg/ml | $322.00 | |||
TMCC3 Antibody (D-6) FITC | sc-515583 FITC | 200 µg/ml | $336.00 | |||
TMCC3 Antibody (D-6) PE | sc-515583 PE | 200 µg/ml | $349.00 | |||
TMCC3 Antibody (D-6) Alexa Fluor® 488 | sc-515583 AF488 | 200 µg/ml | $364.00 | |||
TMCC3 Antibody (D-6) Alexa Fluor® 546 | sc-515583 AF546 | 200 µg/ml | $364.00 | |||
TMCC3 Antibody (D-6) Alexa Fluor® 594 | sc-515583 AF594 | 200 µg/ml | $364.00 | |||
TMCC3 Antibody (D-6) Alexa Fluor® 647 | sc-515583 AF647 | 200 µg/ml | $364.00 | |||
TMCC3 Antibody (D-6) Alexa Fluor® 680 | sc-515583 AF680 | 200 µg/ml | $364.00 | |||
TMCC3 Antibody (D-6) Alexa Fluor® 790 | sc-515583 AF790 | 200 µg/ml | $364.00 | |||
TMCC3 (D-6) Neutralizing Peptide | sc-515583 P | 100 µg/0.5 ml | $69.00 |