TLR2 Antibody (A-9): sc-166900
- TLR2 Antibody (A-9) is a mouse monoclonal IgG2a κ, cited in 27 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 762-780 at the C-terminus of TLR2 of human origin
- TLR2 Antibody (A-9) is recommended for detection of TLR2 of human origin by WB, IP, IF and ELISA
- Anti-TLR2 Antibody (A-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TLR2 Antibody (A-9) for WB applications. These reagents are now offered in bundles with TLR2 Antibody (A-9) (see ordering information below).
TLR2 Antibody (A-9) is a mouse monoclonal IgG2a kappa light chain antibody that detects TLR2 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TLR2 (A-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TLR2 plays a crucial role in the immune system by recognizing pathogen-associated molecular patterns, which is essential for initiating inflammatory responses. TLR2 is primarily located on the cell surface of immune cells such as macrophages and dendritic cells, where TLR2 acts as a pattern recognition receptor. TLR2 presence on these cells is vital for detecting a wide range of microbial components, including peptidoglycan from Gram-positive bacteria and lipoproteins, thereby facilitating innate immunity activation. Upon ligand binding, TLR2 dimerizes with TLR1 or TLR6, leading to adaptor protein recruitment and activation of downstream signaling pathways, including the NF-kB pathway, ultimately resulting in pro-inflammatory cytokine production. TLR2 expression is particularly high in peripheral blood leukocytes, highlighting TLR2′s importance in immune response to infections.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TLR2 Antibody (A-9) | sc-166900 | 200 µg/ml | $322.00 | |||
TLR2 Antibody (A-9): m-IgG Fc BP-HRP Bundle | sc-529081 | 200 µg Ab; 10 µg BP | $361.00 | |||
TLR2 Antibody (A-9): m-IgGκ BP-HRP Bundle | sc-521790 | 200 µg Ab, 40 µg BP | $361.00 | |||
TLR2 Antibody (A-9): m-IgG2a BP-HRP Bundle | sc-547256 | 200 µg Ab; 10 µg BP | $361.00 | |||
TLR2 Antibody (A-9) AC | sc-166900 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TLR2 Antibody (A-9) HRP | sc-166900 HRP | 200 µg/ml | $322.00 | |||
TLR2 Antibody (A-9) FITC | sc-166900 FITC | 200 µg/ml | $336.00 | |||
TLR2 Antibody (A-9) PE | sc-166900 PE | 200 µg/ml | $349.00 | |||
TLR2 Antibody (A-9) Alexa Fluor® 488 | sc-166900 AF488 | 200 µg/ml | $364.00 | |||
TLR2 Antibody (A-9) Alexa Fluor® 546 | sc-166900 AF546 | 200 µg/ml | $364.00 | |||
TLR2 Antibody (A-9) Alexa Fluor® 594 | sc-166900 AF594 | 200 µg/ml | $364.00 | |||
TLR2 Antibody (A-9) Alexa Fluor® 647 | sc-166900 AF647 | 200 µg/ml | $364.00 | |||
TLR2 Antibody (A-9) Alexa Fluor® 680 | sc-166900 AF680 | 200 µg/ml | $364.00 | |||
TLR2 Antibody (A-9) Alexa Fluor® 790 | sc-166900 AF790 | 200 µg/ml | $364.00 | |||
TLR2 (A-9) Neutralizing Peptide | sc-166900 P | 100 µg/0.5 ml | $69.00 |