TIMP-1 Antibody (G-6): sc-365905
- TIMP-1 Antibody (G-6) is a mouse monoclonal IgG1 κ TIMP-1 antibody, cited in 31 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 172-207 near the C-terminus of TIMP-1 of human origin
- TIMP-1 Antibody (G-6) is recommended for detection of TIMP-1 of human origin by WB, IP, IF and ELISA
- Anti-TIMP-1 Antibody (G-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for TIMP-1 Antibody (G-6) for WB applications. This reagent is now offered in a bundle with TIMP-1 Antibody (G-6) (see ordering information below).
QUICK LINKS
TIMP-1 Antibody (G-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects TIMP-1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TIMP-1 Antibody (G-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. TIMP-1 plays a crucial role in regulating extracellular matrix remodeling by inhibiting metalloproteinases, which are enzymes responsible for degrading various components of the extracellular matrix. This function is particularly important in processes such as wound healing, tissue repair, and cancer progression, where maintaining balance between matrix degradation and synthesis is vital for tissue integrity. TIMP-1 interacts with other tissue inhibitors of metalloproteinases, including TIMP-2, TIMP-3, and TIMP-4, which further underscores TIMP-1′s significance in modulating metalloproteinase activity and influencing cellular behaviors. TIMP-1 expression is regulated by various factors, including parathyroid hormone, highlighting TIMP-1′s involvement in complex signaling pathways that govern cellular responses in different physiological and pathological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TIMP-1 Antibody (G-6) | sc-365905 | 200 µg/ml | $322.00 | |||
TIMP-1 Antibody (G-6): m-IgG Fc BP-HRP Bundle | sc-525907 | 200 µg Ab; 10 µg BP | $361.00 | |||
TIMP-1 Antibody (G-6) AC | sc-365905 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TIMP-1 Antibody (G-6) HRP | sc-365905 HRP | 200 µg/ml | $322.00 | |||
TIMP-1 Antibody (G-6) FITC | sc-365905 FITC | 200 µg/ml | $336.00 | |||
TIMP-1 Antibody (G-6) PE | sc-365905 PE | 200 µg/ml | $349.00 | |||
TIMP-1 Antibody (G-6) Alexa Fluor® 488 | sc-365905 AF488 | 200 µg/ml | $364.00 | |||
TIMP-1 Antibody (G-6) Alexa Fluor® 546 | sc-365905 AF546 | 200 µg/ml | $364.00 | |||
TIMP-1 Antibody (G-6) Alexa Fluor® 594 | sc-365905 AF594 | 200 µg/ml | $364.00 | |||
TIMP-1 Antibody (G-6) Alexa Fluor® 647 | sc-365905 AF647 | 200 µg/ml | $364.00 | |||
TIMP-1 Antibody (G-6) Alexa Fluor® 680 | sc-365905 AF680 | 200 µg/ml | $364.00 | |||
TIMP-1 Antibody (G-6) Alexa Fluor® 790 | sc-365905 AF790 | 200 µg/ml | $364.00 | |||
TIMP-1 (G-6) Neutralizing Peptide | sc-365905 P | 100 µg/0.5 ml | $69.00 |