Thy-1/CD90 Antibody (AS74): sc-52790
- Thy-1/CD90 Antibody (AS74) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against thymocytes of rat origin
- recommended for detection of Thy-1 of mouse and rat origin by WB and IP
- See Thy-1/CD90 (aTHy-1A1): sc-53456 for Thy-1/CD90 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Thy-1/CD90 Antibody (AS74) for WB applications. These reagents are now offered in bundles with Thy-1/CD90 Antibody (AS74) (see ordering information below).
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SEE ALSO...
Thy-1 Antibody (AS74) is a mouse monoclonal IgG2a antibody that detects Thy-1 in mouse and rat samples through applications such as western blotting (WB) and immunoprecipitation (IP). Thy-1 is a phosphatidyl-anchored cell surface glycoprotein that plays a crucial role in cell adhesion and signaling, particularly in the context of hematopoietic stem cells. Thy-1 presence on the surface of these cells is vital for their identification and isolation, as Thy-1 helps to distinguish them from other cell types within the bone marrow. Thy-1 interaction with various ligands is essential for maintaining the stem cell niche and regulating hematopoiesis, making Thy-1 a key player in both normal physiology and pathological conditions, such as graft versus host disease. Anti-Thy-1 antibody (AS74) enables researchers to effectively study the dynamics of stem cell populations and their implications in regenerative medicine and transplantation therapies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Thy-1/CD90 Antibody (AS74) References:
- The Thy-1/Thy-1 ligand interaction is involved in binding of melanoma cells to activated Thy-1- positive microvascular endothelial cells. | Saalbach, A., et al. 2002. Microvasc Res. 64: 86-93. PMID: 12074634
- The characterization of a specific Thy-1 molecular epitope expressed on rat mesangial cells. | Morioka, T., et al. 2004. Kidney Int. 66: 2214-23. PMID: 15569310
- Thy-1 supports adhesion of mouse thymocytes to thymic epithelial cells through a Ca2(+)-independent mechanism. | He, HT., et al. 1991. J Exp Med. 173: 515-8. PMID: 1671083
- Thy-1 as a potential novel diagnostic marker for gastrointestinal stromal tumors. | Oikonomou, D., et al. 2007. J Cancer Res Clin Oncol. 133: 951-5. PMID: 17534660
- Brimonidine protects against loss of Thy-1 promoter activation following optic nerve crush. | Dai, Y., et al. 2013. BMC Ophthalmol. 13: 26. PMID: 23805828
- Thy-1 is a differentiation antigen that characterizes immature murine erythroid and myeloid hematopoietic progenitors. | Miller, BA., et al. 1985. J Cell Physiol. 123: 25-32. PMID: 2857726
- Culture and characterization of murine dendritic Thy-1+ epidermal cells. | Caughman, SW., et al. 1986. J Invest Dermatol. 86: 615-24. PMID: 2872251
- Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. | Kroczek, RA., et al. Nature. 322: 181-4. PMID: 2873512
- Ectopic expression of Thy-1 in the kidneys of transgenic mice induces functional and proliferative abnormalities. | Kollias, G., et al. 1987. Cell. 51: 21-31. PMID: 2888537
- Expression of Thy-1 on human hematopoietic progenitor cells. | Craig, W., et al. 1993. J Exp Med. 177: 1331-42. PMID: 7683034
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thy-1/CD90 Antibody (AS74) | sc-52790 | 200 µg/ml | $322.00 | |||
Thy-1/CD90 Antibody (AS74): m-IgG Fc BP-HRP Bundle | sc-536863 | 200 µg Ab; 10 µg BP | $361.00 | |||
Thy-1/CD90 Antibody (AS74): m-IgGκ BP-HRP Bundle | sc-534030 | 200 µg Ab; 40 µg BP | $361.00 | |||
Thy-1/CD90 Antibody (AS74): m-IgG2a BP-HRP Bundle | sc-547887 | 200 µg Ab; 10 µg BP | $361.00 |