Thrombospondin 2 Antibody (4): sc-136238
- Thrombospondin 2 Antibody (4) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- raised against amino acids 173-295 of Thrombospondin 2 of human origin
- recommended for detection of Thrombospondin 2 of mouse, rat and human origin by WB, IP and IF
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Thrombospondin 2 Antibody (4) for WB applications. These reagents are now offered in bundles with Thrombospondin 2 Antibody (4) (see ordering information below).
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Thrombospondin 2 Antibody (4) is a mouse monoclonal IgG1 antibody that detects Thrombospondin 2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Thrombospondin 2 is a member of the thrombospondin family of glycoproteins, which are crucial for various biological processes, including cell adhesion, migration, and the regulation of angiogenesis. Thrombospondin 2 is primarily located in the extracellular matrix, where anti-Thrombospondin 2 antibody (4) can detect its significant role in tissue repair and development. Thrombospondin 2′s presence in the extracellular matrix is vital as this protein facilitates interactions between cells and their surrounding environment, influencing cellular behavior and tissue architecture. Thrombospondin 2 is known to interact with several other proteins, including integrins and growth factors, which further underscores Thrombospondin 2′s importance in modulating cellular responses during wound healing and inflammation. Thrombospondin 2 (4) monoclonal antibody serves as an essential tool for researchers studying these complex biological processes and the role of thrombospondins in health and disease.
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Thrombospondin 2 Antibody (4) References:
- Role of thrombospondin‑1 and thrombospondin‑2 in cardiovascular diseases (Review). | Zhang, K., et al. 2020. Int J Mol Med. 45: 1275-1293. PMID: 32323748
- Thrombospondin-2 spatiotemporal expression in skeletal fractures. | Zondervan, RL., et al. 2021. J Orthop Res. 39: 30-41. PMID: 32437051
- Transcriptomics Identify Thrombospondin-2 as a Biomarker for NASH and Advanced Liver Fibrosis. | Kozumi, K., et al. 2021. Hepatology. 74: 2452-2466. PMID: 34105780
- Serum Thrombospondin-2 Levels Are Closely Associated With the Severity of Metabolic Syndrome and Metabolic Associated Fatty Liver Disease. | Wu, X., et al. 2022. J Clin Endocrinol Metab. 107: e3230-e3240. PMID: 35532410
- Thrombospondin-2 acts as a critical regulator of cartilage regeneration: A review. | Niu, J., et al. 2023. Medicine (Baltimore). 102: e33651. PMID: 37115081
- Thrombospondin-2 Couples Pressure-Promoted Chondrogenesis through NF-κB Signaling. | Niu, J., et al. 2023. Tissue Eng Regen Med. 20: 753-766. PMID: 37219820
- Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2. | Liu, Q., et al. 2023. Stem Cell Res Ther. 14: 234. PMID: 37667335
- Molecular mechanisms of Thrombospondin-2 modulates tumor vasculogenic mimicry by PI3K/AKT/mTOR signaling pathway. | Huang, J., et al. 2023. Biomed Pharmacother. 167: 115455. PMID: 37696083
- Thrombospondin 2 is a key determinant of fibrogenesis in non-alcoholic fatty liver disease. | Kimura, T., et al. 2024. Liver Int. 44: 483-496. PMID: 38010940
- Targeting thrombospondin-2 retards liver fibrosis by inhibiting TLR4-FAK/TGF-β signaling. | Zhang, N., et al. 2024. JHEP Rep. 6: 101014. PMID: 38379585
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Thrombospondin 2 Antibody (4) | sc-136238 | 200 µg/ml | $316.00 | |||
Thrombospondin 2 Antibody (4): m-IgG Fc BP-HRP Bundle | sc-539901 | 200 µg Ab; 10 µg BP | $354.00 | |||
Thrombospondin 2 Antibody (4): m-IgG1 BP-HRP Bundle | sc-541774 | 200 µg Ab; 20 µg BP | $354.00 |