Thrombospondin 2 Inhibitors
Thrombospondin 2 Inhibitors belong to a class of chemical compounds that primarily target a specific protein known as thrombospondin 2 (TSP-2). Thrombospondins are a family of multifunctional extracellular matrix glycoproteins that play essential roles in various physiological processes, including cell adhesion, tissue remodeling, and angiogenesis. TSP-2, in particular, is a member of this family and is associated with diverse biological functions. Thrombospondin 2 Inhibitors are designed to modulate the activity of TSP-2 by preventing its interactions with other cellular proteins or receptors, thus influencing downstream signaling pathways.
The development of Thrombospondin 2 Inhibitors stems from the recognition of TSP-2's involvement in pathological conditions and disease progression. By inhibiting TSP-2, these compounds may have the potential to impact cellular processes such as cell migration, proliferation, and angiogenesis, which are critical in cancer metastasis, tissue fibrosis, and various other diseases. Thrombospondin 2 Inhibitors are thus a subject of intense research and drug development efforts aimed at elucidating their mechanisms of action.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a major component of green tea. It may inhibit TSP-2 expression by affecting signaling pathways related to cellular proliferation and apoptosis, possibly contributing to its known anti-angiogenic effects. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $55.00 $114.00 $206.00 $714.00 | 6 | |
Silibinin is a compound found in milk thistle. It may downregulate TSP-2 expression by modulating cellular signaling pathways involved in inflammation and oxidative stress, potentially impacting TSP-2 related functions. | ||||||
Baicalin | 21967-41-9 | sc-204638 sc-204638A sc-204638B sc-204638C | 1 mg 25 mg 1 g 5 g | $56.00 $112.00 $224.00 $265.00 | 4 | |
Baicalin is a flavonoid found in the Chinese herb Scutellaria baicalensis. It may suppress TSP-2 expression by modulating anti-inflammatory and antioxidative signaling pathways, potentially impacting cellular responses. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin is a flavonoid found in various fruits and vegetables. It may reduce TSP-2 expression by affecting cellular signaling pathways related to inflammation and oxidative stress, possibly contributing to its known effects. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin is a flavonoid present in many plants. It may downregulate TSP-2 expression through its anti-inflammatory and antioxidative properties, potentially impacting cellular processes and responses. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Ellagic acid is a polyphenolic compound found in berries and nuts. It may inhibit TSP-2 expression by modulating various cellular signaling pathways, potentially leading to anti-inflammatory and antioxidative effects. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Kaempferol is a flavonoid present in many fruits and vegetables. It may reduce TSP-2 expression by affecting signaling pathways related to inflammation and oxidative stress, potentially contributing to its known health benefits. | ||||||