Thimet oligopeptidase Antibody (D-11): sc-515659

Thimet oligopeptidase Antibody (D-11) is a mouse monoclonal IgG1 antibody that detects Thimet oligopeptidase in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Thimet oligopeptidase, also known as soluble metallo-endopeptidase, plays a crucial role in the degradation of cytoplasmic peptides, particularly neuropeptides that are less than 20 amino acids in length, which is essential for maintaining cellular homeostasis and regulating various physiological processes. This protein is primarily located in the cytoplasm and is highly expressed in the testis, but can also be found in the liver, lung, and kidney, indicating diverse functional roles across different tissues. The gene encoding Thimet oligopeptidase is mapped to chromosome 19q13.3, and Thimet oligopeptidase′s ability to degrade the β-Amyloid precursor protein and generate amyloidogenic fragments highlights its significance in neurodegenerative diseases. With versatile applications and critical biological functions, anti-Thimet oligopeptidase antibody (D-11) serves as an invaluable tool for researchers studying peptide metabolism and related pathways.

The preferred Thimet oligopeptidase antibody is Thimet oligopeptidase Antibody (4D6): sc-53565.