TGF beta Receptor 2/TGFBR2 Antibody (C-4): sc-17791
- TGF beta Receptor 2/TGFBR2 Antibody (C-4) is a mouse monoclonal IgG1 κ TGF beta Receptor 2/TGFBR2 antibody, cited in 37 publications, provided at 200 µg/ml
- raised against amino acids 1-567 representing full length TFGβ RII of human origin
- TGF beta Receptor 2/TGFBR2 Antibody (C-4) is recommended for detection of TGFβ RII of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-TGF beta Receptor 2/TGFBR2 Antibody (C-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for TGF beta Receptor 2/TGFBR2 Antibody (C-4) for WB and IHC(P) applications. These reagents are now offered in bundles with TGF beta Receptor 2/TGFBR2 Antibody (C-4) (see ordering information below).
QUICK LINKS
TGFβ RII Antibody (C-4) is a mouse monoclonal IgG1 kappa light chain antibody specifically designed to detect the transforming growth factor beta receptor type II (TGFβ RII), also known as TGFBR2, across human, mouse, and rat species. TGFβ RII monoclonal antibody (C-4) targets the full-length human TGFβ RII protein, encompassing amino acids 1-567, and is effective in various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TGFβ RII is a critical transmembrane protein that plays a pivotal role in the TGFβ signaling pathway, which regulates numerous cellular processes such as proliferation, differentiation, and apoptosis. By binding to TGFβ ligands, TGFβ RII initiates the phosphorylation of type I receptors, thereby activating downstream Smad proteins that modulate gene expression. This signaling pathway is essential for maintaining cellular homeostasis and has significant implications in developmental biology, immune regulation, and cancer progression. Dysregulation of TGFβ RII function is associated with various diseases, including fibrosis, autoimmune disorders, and tumor metastasis, highlighting its importance as a therapeutic target. anti-TGFβ RII antibody (C-4) is available in both non-conjugated and conjugated forms, such as horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and Alexa Fluor® variants, providing versatile options for researchers. Additionally, TGFβ RII (C-4) antibody is suitable for detecting both isoforms of TGFβ RII, which arise from alternative splicing and are encoded by a gene located on human chromosome 3. TGFβ RII monoclonal antibody (C-4) supports advancements in understanding and targeting the TGFβ signaling axis in various biological and pathological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TGF beta Receptor 2/TGFBR2 Antibody (C-4) | sc-17791 | 200 µg/ml | $322.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4): m-IgG Fc BP-HRP Bundle | sc-526570 | 200 µg Ab; 10 µg BP | $361.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4): m-IgG1 BP-HRP Bundle | sc-531943 | 200 µg Ab; 20 µg BP | $361.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) AC | sc-17791 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) HRP | sc-17791 HRP | 200 µg/ml | $322.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) FITC | sc-17791 FITC | 200 µg/ml | $336.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) PE | sc-17791 PE | 200 µg/ml | $349.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) Alexa Fluor® 488 | sc-17791 AF488 | 200 µg/ml | $364.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) Alexa Fluor® 546 | sc-17791 AF546 | 200 µg/ml | $364.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) Alexa Fluor® 594 | sc-17791 AF594 | 200 µg/ml | $364.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) Alexa Fluor® 647 | sc-17791 AF647 | 200 µg/ml | $364.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) Alexa Fluor® 680 | sc-17791 AF680 | 200 µg/ml | $364.00 | |||
TGF beta Receptor 2/TGFBR2 Antibody (C-4) Alexa Fluor® 790 | sc-17791 AF790 | 200 µg/ml | $364.00 |