Date published: 2025-10-25

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TGF β RI Antibodies

Santa Cruz Biotechnology features a diverse variety of TGF β RI monoclonal antibodies for research focused on understanding transforming growth factor beta receptor type I. TGF β RI Antibodies are available for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).Transforming growth factor beta receptor type I mediates the effects of TGF-β, a key regulator of cell growth, differentiation, and immune response. TGF β RI plays a significant role in various biological processes, including tissue repair, fibrosis, and immune regulation, making it an important target for research in cancer, autoimmune diseases, and developmental biology. Understanding the signaling pathways involving TGF β RI can provide insights into therapeutic strategies for a range of diseases. Research has shown that TGF β RI signaling dysfunction contributes to numerous pathological conditions, from fibrotic disorders to cancer progression. Recent studies have highlighted the importance of TGF β RI in embryonic development and tissue homeostasis. Investigating TGF β RI expression patterns and activation mechanisms continues to reveal new potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of TGF β RI biology and its therapeutic applications.

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TGF β RI Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TGF beta Receptor 1/TGFBR1 Antibody (RM0016-3A11)

sc-101574rat IgG2(m)WB, IF, IHC(P)m
24
(6)

TGF beta Receptor 1/TGFBR1 Antibody (D-1)

sc-518018mouse IgG2a κ26-125 (h)WB, IP, IF, ELISAh
13
(3)

TGF beta Receptor 1/TGFBR1 Antibody (B-7)

sc-518045mouse IgG1 κ26-125 (h)WB, IP, IF, ELISAh
2
(1)

TGF beta Receptor 1/TGFBR1 Antibody (C-12)

sc-518086mouse IgG2b κ26-125 (h)WB, IP, IF, ELISAm, r, h
4
(1)

TGF β RI CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TGF beta Receptor 1/TGFBR1 CRISPR/Cas9 KO Plasmid (h)

sc-400153hGene KnockoutGFP0
(0)

TGF beta Receptor 1/TGFBR1 HDR Plasmid (h)

sc-400153-HDRhHomology Directed RepairPuromycin0
(0)

TGF beta Receptor 1/TGFBR1 Double Nickase Plasmid (h)

sc-400153-NIChGene KnockoutPuromycin0
(0)

TGF beta Receptor 1/TGFBR1 Double Nickase Plasmid (h2)

sc-400153-NIC-2hGene KnockoutPuromycin0
(0)

TGF beta Receptor 1/TGFBR1 CRISPR/Cas9 KO Plasmid (m)

sc-423370mGene KnockoutGFP0
(0)

TGF beta Receptor 1/TGFBR1 HDR Plasmid (m)

sc-423370-HDRmHomology Directed RepairPuromycin0
(0)

TGF beta Receptor 1/TGFBR1 Double Nickase Plasmid (m)

sc-423370-NICmGene KnockoutPuromycin0
(0)

TGF beta Receptor 1/TGFBR1 Double Nickase Plasmid (m2)

sc-423370-NIC-2mGene KnockoutPuromycin0
(0)

TGF β RI CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TGF beta Receptor 1/TGFBR1 CRISPR Activation Plasmid (h)

sc-400153-ACThGene ActivationPuro, Blast, Hygro0
(0)

TGF beta Receptor 1/TGFBR1 CRISPR Activation Plasmid (h2)

sc-400153-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

TGF beta Receptor 1/TGFBR1 Lentiviral Activation Particles (h)

sc-400153-LAChGene ActivationPuro, Blast, Hygro0
(0)

TGF beta Receptor 1/TGFBR1 Lentiviral Activation Particles (h2)

sc-400153-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

TGF beta Receptor 1/TGFBR1 CRISPR Activation Plasmid (m)

sc-423370-ACTmGene ActivationPuro, Blast, Hygro0
(0)

TGF beta Receptor 1/TGFBR1 CRISPR Activation Plasmid (m2)

sc-423370-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

TGF beta Receptor 1/TGFBR1 Lentiviral Activation Particles (m)

sc-423370-LACmGene ActivationPuro, Blast, Hygro0
(0)

TGF beta Receptor 1/TGFBR1 Lentiviral Activation Particles (m2)

sc-423370-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

TGF β RI siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TGF beta Receptor 1/TGFBR1 siRNA (h)

sc-40222hGene SilencingN/A
11
(0)

TGF beta Receptor 1/TGFBR1 shRNA Plasmid (h)

sc-40222-SHhGene SilencingPuromycin
11
(0)

TGF beta Receptor 1/TGFBR1 shRNA (h) Lentiviral Particles

sc-40222-VhGene SilencingPuromycin
11
(0)

TGF beta Receptor 1/TGFBR1 siRNA (m)

sc-40223mGene SilencingN/A
3
(0)

TGF beta Receptor 1/TGFBR1 shRNA Plasmid (m)

sc-40223-SHmGene SilencingPuromycin
3
(0)

TGF beta Receptor 1/TGFBR1 shRNA (m) Lentiviral Particles

sc-40223-VmGene SilencingPuromycin
3
(0)