TFIID/TATA Binding Protein/TBP Antibody (C-8): sc-374035
- TFIID/TATA Binding Protein/TBP Antibody (C-8) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 12-37 at the N-terminus of TFIID of human origin
- recommended for detection of TFIID (TBP) p36 of mouse, rat, human and origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and avian
- TransCruz reagent for ChIP application (sc-374035 X, 200 µg/0.1 ml)
- See TFIID/TATA Binding Protein/TBP (58C9): sc-421 for TFIID/TATA Binding Protein/TBP antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TFIID/TATA Binding Protein/TBP Antibody (C-8) for WB applications. These reagents are now offered in bundles with TFIID/TATA Binding Protein/TBP Antibody (C-8) (see ordering information below).
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SEE ALSO...
TFIID Antibody (C-8) is a mouse monoclonal IgG1 antibody that detects TFIID in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TFIID plays a crucial role in the initiation of transcription by RNA polymerase II, serving as a key component of the pre-initiation complex that assembles at the core promoter region of protein-coding genes. The TATA-binding protein (TBP), a subunit of TFIID, is essential for recognizing and binding to the TATA box, a conserved DNA sequence located approximately 25-30 base pairs upstream of the transcription start site. This interaction is vital for the recruitment of other transcription factors and RNA polymerase II, ultimately facilitating the transcription of genes necessary for various cellular functions. The structural integrity of TFIID, particularly the highly conserved 180 amino acid C-terminal domain of TBP, is critical for its function, as any alterations can disrupt the formation of the transcription complex and lead to impaired gene expression. Anti-TFIID antibody (C-8) is an invaluable tool for researchers studying transcriptional regulation and its implications in cellular processes and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TFIID/TATA Binding Protein/TBP Antibody (C-8) | sc-374035 | 200 µg/ml | $322.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-537908 | 200 µg Ab; 10 µg BP | $361.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-535372 | 200 µg Ab; 40 µg BP | $361.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (C-8): m-IgG1 BP-HRP Bundle | sc-545439 | 200 µg Ab; 20 µg BP | $361.00 | |||
TFIID/TATA Binding Protein/TBP (C-8) Neutralizing Peptide | sc-374035 P | 100 µg/0.5 ml | $69.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (C-8) X | sc-374035 X | 200 µg/0.1 ml | $322.00 |