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TFIID Antibody (1TB18) is a mouse monoclonal IgG1 antibody that detects TFIID in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. TFIID plays a crucial role in the initiation of transcription by RNA polymerase II, serving as a key component of the pre-initiation complex that assembles at the core promoter region of protein-coding genes. This complex is essential for the accurate and efficient transcription of genes, as TFIID binds to the TATA box, a conserved DNA sequence located approximately 25-30 base pairs upstream of the transcription start site. The TATA-binding protein (TBP), a subunit of TFIID, contains a highly-conserved C-terminal domain of 180 amino acids that is critical for recognizing and binding to the TATA element. The interaction of TFIID with other basal transcription factors and RNA polymerase II is vital for the regulation of gene expression, making TFIID a significant player in cellular processes such as development, differentiation, and response to environmental signals. Anti-TFIID antibody (1TB18) enables researchers to gain insights into the dynamics of transcription regulation and its implications in various biological contexts.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TFIID/TATA Binding Protein/TBP Antibody (1TB18) | sc-56794 | 200 µg/ml | $316.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (1TB18): m-IgG Fc BP-HRP Bundle | sc-537120 | 200 µg Ab; 10 µg BP | $354.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (1TB18): m-IgGκ BP-HRP Bundle | sc-534312 | 200 µg Ab; 40 µg BP | $354.00 | |||
TFIID/TATA Binding Protein/TBP Antibody (1TB18): m-IgG1 BP-HRP Bundle | sc-545015 | 200 µg Ab; 20 µg BP | $354.00 |