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TAF II p70 Antibody (585D4a) is a mouse monoclonal IgG1 antibody that detects TAF II p70 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). TAF II p70, also known as TAF6, TAF2E, TAFII70, TAFII80, or TAFII85, plays a crucial role in the basal transcription complex, facilitating the assembly of the preinitiation complex by interacting with various TBP-associated factors. TAF II p70 is essential for the regulation of gene expression, as TAF II p70 directly binds to the TATA-binding protein and other TAFs, forming a heterodimer with TAF II p31 that may act as a coactivator for the tumor suppressor protein p53. The presence of multiple isoforms of TAF II p70, resulting from alternative splicing, adds a layer of complexity to function and regulation, making TAF II p70 a significant focus of study in understanding transcriptional control mechanisms. Anti-TAF II p70 antibody (585D4a) is an invaluable tool for researchers investigating the dynamics of transcription regulation and the intricate interactions within the transcription machinery.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TAF II p70 Antibody (585D4a) | sc-81124 | 100 µg/ml | $339.00 |