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TAF II p100 Antibody (H-3) is a mouse monoclonal IgG3 antibody that detects TAF II p100 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TAF II p100, also known as TAF5 or TAFII100, is a critical component of the TFIID complex, which is essential for the initiation of transcription by RNA polymerase II. TAF II p100 plays a pivotal role in forming the scaffold necessary for the assembly of the TFIID complex, ensuring that other transcription factors can effectively bind to the promoter region of genes. The presence of six WD40 repeats at the C-terminus of TAF II p100 contributes to structural stability and interaction capabilities, while flexible dimerization potential at the N-terminus allows for dynamic interactions with other TAFs, enhancing the overall stability of the transcriptional machinery. Understanding the function and interactions of TAF II p100 is vital, as TAF II p100 not only facilitates the transcription process but also influences gene expression regulation, which is crucial for cellular function and response to environmental signals.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TAF II p100 Antibody (H-3) | sc-374644 | 200 µg/ml | $322.00 | |||
TAF II p100 Antibody (H-3): m-IgG3 BP-HRP Bundle | sc-550453 | 200 µg Ab; 40 µg BP | $361.00 | |||
TAF II p100 (H-3) Neutralizing Peptide | sc-374644 P | 100 µg/0.5 ml | $69.00 |