T Cell Marker Antibody (KEN-5): sc-59373
- T Cell Marker Antibody (KEN-5) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- raised against thymocytes of rabbit origin
- T Cell Marker Antibody (KEN-5) is recommended for detection of thymocytes of rabbit origin by WB, IP, IF and FCM; may cross-react with mesenteric lymph node cells; non cross-reactive with rabbit CD5 transfectants
- Anti-T Cell Marker Antibody (KEN-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for T Cell Marker Antibody (KEN-5) for WB applications. These reagents are now offered in bundles with T Cell Marker Antibody (KEN-5) (see ordering information below).
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T Cell Marker Antibody (KEN-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects the T Cell Marker protein of rabbit origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). T Cell Marker (KEN-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. T cells, which are a crucial component of the immune system, are primarily responsible for cell-mediated immunity and are characterized by the presence of the T cell receptor (TCR) on their surface. The TCR is essential for recognizing antigens presented by other cells, which is vital for initiating an immune response. T cells originate in the bone marrow and undergo maturation in the thymus before circulating to peripheral lymphoid tissues such as the spleen, tonsils, and lymph nodes. The presence of pan T cell markers, including CD2, CD3, CD5, and CD7, is critical for identifying mature T cells, with CD2 and CD3 being the most specific markers. Notably, the expression of these markers can vary in different pathological conditions, such as the downregulation of CD7 in acute infectious mononucleosis and the unique expression patterns observed in Sezary syndrome, a type of T cell lymphoma. The versatility of T Cell Marker (KEN-5) monoclonal antibody in various applications makes this product an invaluable tool for researchers studying T cell biology and related immunological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
T Cell Marker Antibody (KEN-5) References:
- CD5 expression in human B-cell populations. | Youinou, P., et al. 1999. Immunol Today. 20: 312-6. PMID: 10379049
- Down-regulation of pan-T-cell antigens, particularly CD7, in acute infectious mononucleosis. | Weisberger, J., et al. 2003. Am J Clin Pathol. 120: 49-55. PMID: 12866372
- Myeloid differentiation of purified CD34+ cells after stimulation with recombinant human granulocyte-monocyte colony-stimulating factor (CSF), granulocyte-CSF, monocyte-CSF, and interleukin-3. | Egeland, T., et al. 1991. Blood. 78: 3192-9. PMID: 1720697
- The structural biology of CD2. | Moingeon, P., et al. 1989. Immunol Rev. 111: 111-44. PMID: 2576417
- [Masking of pan-T-cell markers in patients with autoimmune diseases]. | Grunow, R., et al. 1987. Dermatol Monatsschr. 173: 390-9. PMID: 3498654
- CD3: structure, function, and role of immunostaining in clinical practice. | Chetty, R. and Gatter, K. 1994. J Pathol. 173: 303-7. PMID: 7525907
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
T Cell Marker Antibody (KEN-5) | sc-59373 | 200 µg/ml | $322.00 | |||
T Cell Marker Antibody (KEN-5): m-IgG Fc BP-HRP Bundle | sc-526933 | 200 µg Ab; 10 µg BP | $361.00 | |||
T Cell Marker Antibody (KEN-5): m-IgG1 BP-HRP Bundle | sc-532306 | 200 µg Ab; 20 µg BP | $361.00 | |||
T Cell Marker Antibody (KEN-5) AC | sc-59373 AC | 500 µg/ml, 25% agarose | $424.00 | |||
T Cell Marker Antibody (KEN-5) HRP | sc-59373 HRP | 200 µg/ml | $322.00 | |||
T Cell Marker Antibody (KEN-5) FITC | sc-59373 FITC | 200 µg/ml | $336.00 | |||
T Cell Marker Antibody (KEN-5) PE | sc-59373 PE | 200 µg/ml | $349.00 | |||
T Cell Marker Antibody (KEN-5) Alexa Fluor® 488 | sc-59373 AF488 | 200 µg/ml | $364.00 | |||
T Cell Marker Antibody (KEN-5) Alexa Fluor® 546 | sc-59373 AF546 | 200 µg/ml | $364.00 | |||
T Cell Marker Antibody (KEN-5) Alexa Fluor® 594 | sc-59373 AF594 | 200 µg/ml | $364.00 | |||
T Cell Marker Antibody (KEN-5) Alexa Fluor® 647 | sc-59373 AF647 | 200 µg/ml | $364.00 | |||
T Cell Marker Antibody (KEN-5) Alexa Fluor® 680 | sc-59373 AF680 | 200 µg/ml | $364.00 | |||
T Cell Marker Antibody (KEN-5) Alexa Fluor® 790 | sc-59373 AF790 | 200 µg/ml | $364.00 |