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Syntenin-1 Antibody (E-3) is a mouse monoclonal IgM antibody that detects syntenin-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Syntenin-1 plays a crucial role in cellular signaling and structural organization, primarily functioning as an adaptor protein that links syndecans to cytoskeletal components and downstream signaling pathways. This interaction is vital for maintaining cellular architecture and facilitating communication between the extracellular matrix and the cytoplasm, which is essential for processes such as cell migration, proliferation, and differentiation. The presence of PDZ domains in syntenin-1 allows binding to specific carboxy-terminal sequences of syndecans, thereby influencing various signaling cascades. Additionally, syntenin-1 colocalizes with immature forms of proTGF-alpha, highlighting syntenin-1′s involvement in growth factor signaling. Anti-syntenin-1 antibody (E-3)′s ability to recognize syntenin-1 across multiple species makes this reagent an invaluable tool for researchers studying cellular processes and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
syntenin-1 Antibody (E-3) | sc-515507 | 200 µg/ml | $322.00 | |||
syntenin-1 (E-3) Neutralizing Peptide | sc-515507 P | 100 µg/0.5 ml | $69.00 |