Syntaxin 3 Antibody (D-5): sc-393518
- Syntaxin 3 Antibody (D-5) is a mouse monoclonal IgG1 κ Syntaxin 3 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-33 mapping at the N-terminus of Syntaxin 3 of human origin
- Syntaxin 3 Antibody (D-5) is recommended for detection of Syntaxin 3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Syntaxin 3 Antibody (D-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Syntaxin 3 Antibody (D-5) for WB applications. These reagents are now offered in bundles with Syntaxin 3 Antibody (D-5) (see ordering information below).
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SEE ALSO...
Syntaxin 3 Antibody (D-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects Syntaxin 3 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Syntaxin 3 antibody (D-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Syntaxin 3 plays a crucial role in vesicular transport, essential for eukaryotic cell survival. Syntaxin 3 belongs to the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) family, vital for synaptic vesicle fusion with plasma membrane. Syntaxin 3 localizes to apical plasma membrane, participating in membrane fusion processes of apical trafficking pathways. Proper functioning of Syntaxin 3 is critical for neurite growth and serves as a direct target for arachidonic acid, highlighting significance in neuronal signaling and development. Human Syntaxin 3 exists in two forms, Syntaxin 3A and 3B, while mouse variants include four forms: 3A, 3B, 3C, and 3D, each contributing to diverse cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Syntaxin 3 Antibody (D-5) References:
- Deployment of membrane fusion protein domains during fusion. | Bentz, J. and Mittal, A. 2000. Cell Biol Int. 24: 819-38. PMID: 11067767
- Transmembrane domain length determines intracellular membrane compartment localization of syntaxins 3, 4, and 5. | Watson, RT. and Pessin, JE. 2001. Am J Physiol Cell Physiol. 281: C215-23. PMID: 11401844
- The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells. | ter Beest, MB., et al. 2005. Mol Biol Cell. 16: 5784-92. PMID: 16207812
- Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity. | Low, SH., et al. 2006. Mol Biol Cell. 17: 977-89. PMID: 16339081
- Apical targeting of syntaxin 3 is essential for epithelial cell polarity. | Sharma, N., et al. 2006. J Cell Biol. 173: 937-48. PMID: 16785322
- Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells. | Schillemans, M., et al. 2018. Arterioscler Thromb Vasc Biol. 38: 1549-1561. PMID: 29880488
- Syntaxin-3 is dispensable for basal neurotransmission and synaptic plasticity in postsynaptic hippocampal CA1 neurons. | Shi, S., et al. 2020. Sci Rep. 10: 709. PMID: 31959797
- Syntaxin 3 interacts with serotonin transporter and regulates its function. | Motoike, S., et al. 2021. J Pharmacol Sci. 145: 297-307. PMID: 33712280
- Syntaxin 3 is haplosufficient for long-term photoreceptor survival in the mouse retina. | Perez-Hurtado, M., et al. 2023. Front Ophthalmol (Lausanne). 3: PMID: 37609371
- The syntaxin family of vesicular transport receptors. | Bennett, MK., et al. 1993. Cell. 74: 863-73. PMID: 7690687
- A v-SNARE implicated in intra-Golgi transport. | Nagahama, M., et al. 1996. J Cell Biol. 133: 507-16. PMID: 8636227
- A SNARE involved in protein transport through the Golgi apparatus. | Lowe, SL., et al. 1997. Nature. 389: 881-4. PMID: 9349823
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Syntaxin 3 Antibody (D-5) | sc-393518 | 200 µg/ml | $316.00 | |||
Syntaxin 3 Antibody (D-5): m-IgG Fc BP-HRP Bundle | sc-530478 | 200 µg Ab; 10 µg BP | $354.00 | |||
Syntaxin 3 Antibody (D-5): m-IgGκ BP-HRP Bundle | sc-523976 | 200 µg Ab, 40 µg BP | $354.00 | |||
Syntaxin 3 Antibody (D-5): m-IgG1 BP-HRP Bundle | sc-544074 | 200 µg Ab; 20 µg BP | $354.00 | |||
Syntaxin 3 Antibody (D-5) AC | sc-393518 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Syntaxin 3 Antibody (D-5) HRP | sc-393518 HRP | 200 µg/ml | $316.00 | |||
Syntaxin 3 Antibody (D-5) FITC | sc-393518 FITC | 200 µg/ml | $330.00 | |||
Syntaxin 3 Antibody (D-5) PE | sc-393518 PE | 200 µg/ml | $343.00 | |||
Syntaxin 3 Antibody (D-5) Alexa Fluor® 488 | sc-393518 AF488 | 200 µg/ml | $357.00 | |||
Syntaxin 3 Antibody (D-5) Alexa Fluor® 546 | sc-393518 AF546 | 200 µg/ml | $357.00 | |||
Syntaxin 3 Antibody (D-5) Alexa Fluor® 594 | sc-393518 AF594 | 200 µg/ml | $357.00 | |||
Syntaxin 3 Antibody (D-5) Alexa Fluor® 647 | sc-393518 AF647 | 200 µg/ml | $357.00 | |||
Syntaxin 3 Antibody (D-5) Alexa Fluor® 680 | sc-393518 AF680 | 200 µg/ml | $357.00 | |||
Syntaxin 3 Antibody (D-5) Alexa Fluor® 790 | sc-393518 AF790 | 200 µg/ml | $357.00 |