CD362/SDC2/Syndecan-2 Antibody (F-11): sc-376229

Syndecan-2 Antibody (F-11) is a mouse monoclonal IgM antibody that detects Syndecan-2 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Syndecan-2 antibody (F-11) is specific for an epitope mapping between amino acids 59-95 within an N-terminal extracellular domain of Syndecan-2 of mouse origin. Syndecan-2 (F-11) monoclonal antibody, also known as fibroglycan or HSPG, plays a crucial role in cellular processes by acting as a coreceptor for various growth factors and cytokines, which are essential for cell signaling and communication. Syndecan-2 is predominantly located at the epithelial-mesenchymal interfaces and is highly expressed in areas of active morphogenesis, such as during embryonic development and tissue repair. Anti-Syndecan-2 antibody (F-11) helps researchers study these vital functions in regulating cell behavior, including proliferation, migration, and differentiation, thereby influencing developmental processes and wound healing. Syndecan-2 (F-11) antibody enables research into interactions with other proteins, such as fibroblast growth factors and transforming growth factor-beta, which further underscores Syndecan-2′s importance in modulating cellular responses to the extracellular environment. Syndecan-2 modulates the fibroblast growth factor (FGF) and transforming growth factor-beta (TGF-β) signaling pathways by enhancing ligand-receptor interactions, which are critical for cellular processes such as angiogenesis, tissue remodeling, and epithelial-mesenchymal transition. Anti-Syndecan-2 antibody (F-11) serves as an invaluable tool for researchers studying these complex biological processes and Syndecan-2′s role in health and disease.

The preferred CD362/SDC2/Syndecan-2 antibody is CD362/SDC2/Syndecan-2 Antibody (H-7): sc-365624.