


Syncollin Antibody (D-11) is a mouse monoclonal IgG1 antibody that detects syncollin in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Syncollin, also known as SYL or insulin synthesis-associated protein 1, is a 134 amino acid protein predominantly expressed in pancreatic acinar cells, where syncollin localizes to the membranes of secretory vesicles and the lumenal side of peripheral membranes. This strategic localization is crucial as syncollin plays a significant role in the process of exocytosis, influencing the maturation and concentration of zymogens within zymogen granules, which are essential for proper digestive enzyme secretion. The gene encoding syncollin is located on human chromosome 19, a region known for its high gene density and housing numerous immunoglobulin superfamily members, including various receptors and adhesion molecules. Syncollin′s ability to modulate zymogen granule dynamics underscores syncollin′s importance in pancreatic function and digestive health, making anti-syncollin antibody (D-11) a valuable tool for researchers studying exocytosis and related cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
syncollin Antibody (D-11) | sc-514734 | 200 µg/ml | $322.00 | |||
syncollin Antibody (D-11): m-IgG Fc BP-HRP Bundle | sc-538691 | 200 µg Ab; 10 µg BP | $361.00 | |||
syncollin Antibody (D-11): m-IgGκ BP-HRP Bundle | sc-536353 | 200 µg Ab; 40 µg BP | $361.00 | |||
syncollin Antibody (D-11): m-IgG1 BP-HRP Bundle | sc-545834 | 200 µg Ab; 20 µg BP | $361.00 | |||
syncollin (D-11) Neutralizing Peptide | sc-514734 P | 100 µg/0.5 ml | $69.00 |