Synaptotagmin V Antibody (F-7): sc-398837
- Synaptotagmin V Antibody (F-7) is a mouse monoclonal IgG2a κ Synaptotagmin V antibody provided at 200 µg/ml
- raised against amino acids 57-115 mapping within an internal region of synaptotagmin V of mouse origin
- Synaptotagmin V Antibody (F-7) is recommended for detection of synaptotagmin V of mouse and rat origin by WB, IP, IF and ELISA
- Anti-Synaptotagmin V Antibody (F-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Synaptotagmin V Antibody (F-7) for WB applications. This reagent is now offered in a bundle with Synaptotagmin V Antibody (F-7) (see ordering information below).
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Synaptotagmin V Antibody (F-7) is a mouse monoclonal IgG2a kappa light chain antibody that detects Synaptotagmin V (SYT5) of mouse and rat origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Synaptotagmin V antibody (F-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Synaptotagmin V (F-7) monoclonal antibody recognizes a member of the synaptotagmin family, which consists of integral membrane proteins that play crucial roles in regulating exocytosis and endocytosis, particularly in neurotransmitter release from synaptic vesicles. SYT5 is primarily located in dense-core vesicles, where SYT5 acts as a calcium sensor, facilitating neurotransmitter release in response to calcium influx. This function is vital for synaptic transmission and communication between neurons, making SYT5 essential for proper nervous system function. Additionally, SYT5 interaction with other proteins, such as synaptophysin and complexin, underscores SYT5′s role in the intricate machinery of synaptic vesicle exocytosis. Dysregulation of SYT5 and associated pathways has been implicated in various neurological disorders, highlighting SYT5′s importance in both health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Synaptotagmin V Antibody (F-7) References:
- Analysis of synaptotagmin I-IV messenger RNA expression and developmental regulation in the rat hypothalamus and pituitary. | Xi, D., et al. 1999. Neuroscience. 88: 425-35. PMID: 10197764
- The human synaptotagmin IV gene defines an evolutionary break point between syntenic mouse and human chromosome regions but retains ligand inducibility and tissue specificity. | Ferguson, GD., et al. 2000. J Biol Chem. 275: 36920-6. PMID: 10938284
- Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. | Li, C., et al. 1995. Nature. 375: 594-9. PMID: 7791877
- A third synaptotagmin gene, Syt3, in the mouse. | Hilbush, BS. and Morgan, JI. 1994. Proc Natl Acad Sci U S A. 91: 8195-9. PMID: 8058779
- Expression of synaptotagmin VIII in rat kidney. | Kishore, BK., et al. 1998. Am J Physiol. 275: F131-42. PMID: 9689015
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Synaptotagmin V Antibody (F-7) | sc-398837 | 200 µg/ml | $322.00 | |||
Synaptotagmin V Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-526326 | 200 µg Ab; 10 µg BP | $361.00 | |||
Synaptotagmin V Antibody (F-7) AC | sc-398837 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Synaptotagmin V Antibody (F-7) HRP | sc-398837 HRP | 200 µg/ml | $322.00 | |||
Synaptotagmin V Antibody (F-7) FITC | sc-398837 FITC | 200 µg/ml | $336.00 | |||
Synaptotagmin V Antibody (F-7) PE | sc-398837 PE | 200 µg/ml | $349.00 | |||
Synaptotagmin V Antibody (F-7) Alexa Fluor® 488 | sc-398837 AF488 | 200 µg/ml | $364.00 | |||
Synaptotagmin V Antibody (F-7) Alexa Fluor® 546 | sc-398837 AF546 | 200 µg/ml | $364.00 | |||
Synaptotagmin V Antibody (F-7) Alexa Fluor® 594 | sc-398837 AF594 | 200 µg/ml | $364.00 | |||
Synaptotagmin V Antibody (F-7) Alexa Fluor® 647 | sc-398837 AF647 | 200 µg/ml | $364.00 | |||
Synaptotagmin V Antibody (F-7) Alexa Fluor® 680 | sc-398837 AF680 | 200 µg/ml | $364.00 | |||
Synaptotagmin V Antibody (F-7) Alexa Fluor® 790 | sc-398837 AF790 | 200 µg/ml | $364.00 |