Anti-Synaptotagmin I/II Antibody (H-9) is a mouse monoclonal IgG1 (kappa light chain) Synaptotagmin I/II antibody provided at 200 µg/ml
specific for an epitope mapping between amino acids 301-318 within an internal region of Synaptotagmin I of human origin
Anti-Synaptotagmin I/II Antibody (H-9) is recommended for detection of Synaptotagmin I/II of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-Synaptotagmin I/II Antibody (H-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
blocking peptide, sc-393392 P
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Synaptotagmin I/II (H-9): sc-393392.
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
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Labware ships FedEx Ground free of charge to the contiguous US
Synaptotagmin I/II Antibody (H-9) is a high quality monoclonal Synaptotagmin I/II antibody (also designated Synaptotagmin I/II antibody) suitable for the detection of the Synaptotagmin I/II protein of mouse, rat and human origin. Synaptotagmin I/II Antibody (H-9) is available as both the non-conjugated anti-Synaptotagmin I/II antibody form, as well as multiple conjugated forms of anti-Synaptotagmin I/II antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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