Synaptojanin 1 Antibody (AC1): sc-56966

Synaptojanin 1 Antibody (AC1) is a mouse monoclonal IgG1 antibody that detects synaptojanin 1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Synaptojanin 1 plays a crucial role in the endocytosis of synaptic vesicles, a process essential for neurotransmitter release and synaptic transmission, thereby influencing neuronal communication and plasticity. Anti-synaptojanin 1 antibody (AC1) targets a protein primarily located in the brain, where synaptojanin 1 exists in two major forms: a shorter variant predominantly found in the brain and a longer variant expressed in peripheral tissues. The presence of synaptojanin 1 in the brain underscores its importance in synaptic function and the regulation of the actin cytoskeleton, which is vital for maintaining the structural integrity of neurons and facilitating vesicle trafficking. Additionally, synaptojanin 1 is part of a larger family of synaptojanins that includes synaptojanin 2, which has multiple splice variants, including a brain-specific isoform, further highlighting the complexity and regulatory mechanisms of synaptic vesicle dynamics. Synaptojanin 1 (AC1) monoclonal antibody serves as an invaluable tool for researchers studying synaptic function and related neurological disorders.

The preferred Synaptojanin 1 antibody is Synaptojanin 1 Antibody (5H1): sc-32770.