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Synaptogyrin-4 Antibody (F-11): sc-393912

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Datasheets
  • Synaptogyrin-4 Antibody (F-11) is a mouse monoclonal IgG1 κ Synaptogyrin-4 antibody provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 210-233 at the C-terminus of Synaptogyrin-4 of mouse origin
  • Synaptogyrin-4 Antibody (F-11) is recommended for detection of Synaptogyrin-4 of mouse, rat and human origin by WB, IP, IF and ELISA
  • Anti-Synaptogyrin-4 Antibody (F-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Synaptogyrin-4 Antibody (F-11) for WB applications. These reagents are now offered in bundles with Synaptogyrin-4 Antibody (F-11) (see ordering information below).
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    Synaptogyrin-4 Antibody (F-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects Synaptogyrin-4 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Synaptogyrin-4 antibody (F-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Synaptogyrin-4, encoded by the SYNGR4 gene, consists of 234 amino acids and is an integral membrane protein that plays a crucial role in synaptic vesicle dynamics. Synaptogyrin-4 (F-11) antibody targets proteins primarily localized in presynaptic terminals, where they regulate neurotransmitter release, making them essential for proper synaptic function and communication between neurons. Synaptogyrin-4′s presence in synaptic vesicles highlights its importance in maintaining synaptic integrity and facilitating efficient neurotransmission. Synaptogyrin-4′s interaction with other synaptic proteins, such as synaptophysin, underscores its role in the complex machinery of synaptic transmission. Using Synaptogyrin-4 (F-11) monoclonal antibody can help researchers gain valuable insights into synaptic function mechanisms and underlying neurobiological processes.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Synaptogyrin-4 Antibody (F-11) References:

    1. Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.  |  Belfort, GM. and Kandror, KV. 2003. J Biol Chem. 278: 47971-8. PMID: 12928441
    2. Characterization of synaptogyrin 3 as a new synaptic vesicle protein.  |  Belizaire, R., et al. 2004. J Comp Neurol. 470: 266-81. PMID: 14755516
    3. Essential components for a glutamatergic synapse between Merkel cell and nerve terminal in rats.  |  Hitchcock, IS., et al. 2004. Neurosci Lett. 362: 196-9. PMID: 15158013
    4. Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis.  |  Masliah, E., et al. 2004. J Neuroimmunol. 157: 163-75. PMID: 15579294
    5. Cellugyrin induces biogenesis of synaptic-like microvesicles in PC12 cells.  |  Belfort, GM., et al. 2005. J Biol Chem. 280: 7262-72. PMID: 15590695
    6. Rat retinal dopaminergic neurons: differential maturation of somatodendritic and axonal compartments.  |  Witkovsky, P., et al. 2005. J Comp Neurol. 481: 352-62. PMID: 15593337

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Synaptogyrin-4 Antibody (F-11)

    sc-393912
    200 µg/ml
    $322.00

    Synaptogyrin-4 Antibody (F-11): m-IgG Fc BP-HRP Bundle

    sc-530634
    200 µg Ab; 10 µg BP
    $361.00

    Synaptogyrin-4 Antibody (F-11): m-IgGκ BP-HRP Bundle

    sc-524148
    200 µg Ab, 40 µg BP
    $361.00

    Synaptogyrin-4 Antibody (F-11): m-IgG1 BP-HRP Bundle

    sc-544171
    200 µg Ab; 20 µg BP
    $361.00

    Synaptogyrin-4 Antibody (F-11) AC

    sc-393912 AC
    500 µg/ml, 25% agarose
    $424.00

    Synaptogyrin-4 Antibody (F-11) HRP

    sc-393912 HRP
    200 µg/ml
    $322.00

    Synaptogyrin-4 Antibody (F-11) FITC

    sc-393912 FITC
    200 µg/ml
    $336.00

    Synaptogyrin-4 Antibody (F-11) PE

    sc-393912 PE
    200 µg/ml
    $349.00

    Synaptogyrin-4 Antibody (F-11) Alexa Fluor® 488

    sc-393912 AF488
    200 µg/ml
    $364.00

    Synaptogyrin-4 Antibody (F-11) Alexa Fluor® 546

    sc-393912 AF546
    200 µg/ml
    $364.00

    Synaptogyrin-4 Antibody (F-11) Alexa Fluor® 594

    sc-393912 AF594
    200 µg/ml
    $364.00

    Synaptogyrin-4 Antibody (F-11) Alexa Fluor® 647

    sc-393912 AF647
    200 µg/ml
    $364.00

    Synaptogyrin-4 Antibody (F-11) Alexa Fluor® 680

    sc-393912 AF680
    200 µg/ml
    $364.00

    Synaptogyrin-4 Antibody (F-11) Alexa Fluor® 790

    sc-393912 AF790
    200 µg/ml
    $364.00

    Synaptogyrin-4 (F-11) Neutralizing Peptide

    sc-393912 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-393912 P appropriate for?

    Asked by: jenniferc
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Satisfactory Western blot data of SynaptogyrinSatisfactory Western blot data of Synaptogyrin-4 expression in rat testis and mouse testis tissue extracts. -SCBT QC
    Date published: 2013-03-07
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    Synaptogyrin-4 Antibody (F-11) is rated 5.0 out of 5 by 1.
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