Synapsin Ia/b CRISPR Plasmids (m) mouse Synapsin Ia/b-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

Synapsin Ia/b CRISPR Plasmids (m)

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Datasheets

    • Target species: mouse; for corresponding human product, see Synapsin Ia/b CRISPR Plasmids (h)
    • CRISPR/Cas9 KO Plasmids consists of Synapsin Ia/b-specific 20 nt guide RNA sequences derived from the GeCKO (v2) library
    • For CRISPR gene knockout, gRNA sequences direct the Cas9 protein to induce a site-specific double strand break (DSB) in the genomic DNA
    • Target-specific CRISPR Plasmids for both gene knockout and activation are available. Please refer to the detailed product information in the tabs below
    • Gene knockdown or activation can be assayed using Synapsin Ia/b Antibody (A-8): sc-376623
    • All products are provided as transfection-ready, purified plasmid DNA, except the Lentiviral Activation Particles which have been prepackaged as Lentiviral Particles for use with hard-to-transfect cells

Gene Info

SpeciesGene NameGene IDChromosome LocationIsoform (mRNA) Accession #Protein Accession #OMIM™ Number
MouseSyn120964X A1.3NM_001110780, NM_013680O88935N/A

Hi we would like to activate Rat Synapsin I gene in 1 week rat pups after and before GA exposure. So, we prefers viral/plasmid mediated ready to inject- Synapsin I gene activation system, Could you please suggest the available products for rat model !

Asked by: Hari osuru
Thank you for your question. We do not recommend nor support the use of our CRISPR Lentiviral Activation Particles for in vivo applications. We may be able to offer a custom-designed product specific for the rat gene. And we would be happy to discuss with you further the possible limitations our reagents may have in an in vivo research application. Please call our Technical Service Department toll-free at (800) 457-3801 option 2, or use the live chat on our website.
Answered by: Technical Support
Date published: 2018-11-22
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