survivin Antibody (C-6): sc-374616
- survivin Antibody (C-6) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-29 at the N-terminus of survivin of human origin
- recommended for detection of survivin of human origin by WB, IP, IF, IHC(P) and ELISA
- See survivin (D-8): sc-17779 for survivin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for survivin Antibody (C-6) for WB and IHC(P) applications. These reagents are now offered in bundles with survivin Antibody (C-6) (see ordering information below).
QUICK LINKS
SEE ALSO...
Survivin Antibody (C-6) is a mouse monoclonal IgG1 antibody that detects survivin in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Survivin plays a crucial role in regulating cell division and inhibiting apoptosis, making survivin a significant factor in cancer biology, as survivin overexpression is often associated with tumor progression and resistance to chemotherapy. Survivin is primarily located in the cytoplasm and nucleus of dividing cells, where survivin associates with the mitotic spindle during cell division, ensuring proper chromosomal segregation. Survivin presence in these locations is vital for maintaining cellular integrity and preventing premature cell death, which can lead to uncontrolled cell proliferation. Additionally, survivin interacts with other proteins such as caspases and the inhibitor of apoptosis proteins (IAPs), further underscoring survivin′s importance in the apoptotic pathway and cell cycle regulation. Anti-survivin antibody (C-6) is an essential tool for researchers studying cancer mechanisms and therapeutic targets, providing reliable detection and characterization of this critical protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
survivin Antibody (C-6) | sc-374616 | 200 µg/ml | $316.00 | |||
survivin Antibody (C-6): m-IgG Fc BP-HRP Bundle | sc-540487 | 200 µg Ab; 10 µg BP | $354.00 | |||
survivin Antibody (C-6): m-IgG1 BP-HRP Bundle | sc-542154 | 200 µg Ab; 20 µg BP | $354.00 | |||
survivin (C-6) Neutralizing Peptide | sc-374616 P | 100 µg/0.5 ml | $68.00 |